Author(s)

Killivalavan Govindarasu¹, Kavitha Gnanasekaran², Sathyaseelan Balaraman^3*, Baskaran Iruson⁴, Senthilnathan Krishnamoorthy⁵, Sathyaseelan Balaraman³, Babu Padmaraj², Elayaperumal Manikandan^6,7, Sivakumar Dhananjayan⁸

¹Department of Physics, Bharathiar University, Coimbatore, India.
²P. G. Research & Department of Physics, A. M. Jain College, Meenambakkam, India.
³Department of Physics, University College of Engineering Arni (A Constituent College of Anna University Chennai),Arni, India.
³Department of Physics, University College of Engineering Arni (A Constituent College of Anna University Chennai),Arni,India.
⁴Department of Physics Arignar Anna Govt. Arts College, Cheyyar, Tamil Nadu, India.
⁵Department of Physics, VIT University, Vellore, India.
⁶Department of Physics, Thiruvalluvar University, TUCAS Campus, Thennangur, India.
⁷UNESCO UNISA Africa Chair in Nanosciences & Nanotechnology, College of Graduate Studies, University of South Africa, Muckleneuk Ridge, Pretoria, South Africa.
⁸Department of Physics, Sree Krishna College of Engineering, Unai, Anai, India.

Pure and Cadmium (Cd) doped Cerium oxide nanoparticles (CeNPs) have been synthesised by the simple chemical co-precipitation technique. Cadmium ions of concentrations 1, 3 and 5 mol% were doped to investigate their influence on the structural and optical properties of CeO₂. The synthesised samples have been subjected to X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray (EDX) analysis and high-resolution transmission electron microscopy (HRTEM). The XRD and Raman patterns have witnessed the cubic structure of the cerium oxide nanoparticles. The average particle size of CeO₂ was found to be around 10 nm. SEM image has also ascertained that the grain size of pure CeO₂ appeared is bigger than that of the Cd-doped, which intern indicates the grain growth upon doping. Besides, the antibacterial activity of the cadmium doped cerium oxide nanoparticles against some human pathogens revealed that they have exhibited the maximum zone of inhibition against gram-positive bacteria than the gram-negative species. Further, the cytotoxic effect of Cd-doped CeO₂ sample is examined in cultured (MCF-7, A549 and Hep-2) cell.

Co-Precipitation, XRD, SEM, HRTEM, Antibacterial Activity

Govindarasu, K. , Gnanasekaran, K. , Balaraman, S. , Iruson, B. , Krishnamoorthy, S. , Balaraman, S. , Padmaraj, B. , Manikandan, E. and Dhananjayan, S. (2019) Study on Enhanced Antibacterial and Cytotoxicity of Pure and Cadmium Doped Cerium Oxide against Gram-Positive and Gram-Negative Bacteria. Soft Nanoscience Letters, 9, 1-16. doi: 10.4236/snl.2019.91001.