Author(s)

Abu Bakar Siddik¹, Muhammad Maqsud Hossain², Sanjana Zaman³, Basana Marma⁴, Gias Uddin Ahsan¹, Mohammad Rashed Uzzaman⁵, Arman Hossain², Mohammad Delwer Hossain Hawlader^3*

¹School of Health and Life Sciences, North South University, Dhaka, Bangladesh.
²Genome Research Institute, North South University, Dhaka, Bangladesh.
³Department of Public Health, North South University, Dhaka, Bangladesh.
⁴Plan International Bangladesh, Dhaka, Bangladesh.
⁵School of Business and Economics, North South University, Dhaka, Bangladesh.

Background: The number of reported MDR-TB cases has been increasing in recent years. Objectives: To describe the epidemiological profile of MDR-TB cases in Bangladesh. Design: This was a descriptive cross-sectional study. Settings: The study was conducted among the multi drug resistant tuberculosis patient admitted in the National Institute of Diseases of the Chest and Hospital (NIDCH) Dhaka, Bangladesh. Samples: 148 confirmed cases of MDR-TB. Materials and Methods: Hospital admitted MRD-TB cases were randomly chosen from the above mentioned hospital. Semi-structured and pretested questionnaire were introduced by researcher. Clinical and treatment data i.e. duration of TB drug intake, report of sputum, X-ray and blood test etc. were extracted from the hospital record. Results: Study found, majority of the participants (56.1%) were in the age group of 16 - 30 years. 64.2% of the study subjects were married. Majority of the participants education were whether under primary or primary level. 24.3% participant’s family member and 14.5% of neighbor were having TB. Most common comorbidity were diabetes, pulmonary infection, hearing loss, psychiatric symptoms, chest pain, joint pain etc. 63.5% respondent had high degree of AFB for sputum positivity and more than 98% had positive finding in X-ray chest. On an average ESR was low and also few cases of extremely low ESR were found. 71.6% were under twenty four months regimen. Conclusion: We can conclude that, many possible factors for MDR-TB. There is an urgent need for further study to confirm the exact factors in Bangladesh and address those immediately.

MDR-TB, Risk Factors, Descriptive Study, Epidemiology, Bangladesh

Siddik, A.B., Hossain, M.M., Zaman, S., Marma, B., Ahsan, G.U., Uzzaman, M.R., Hossain, A. and Hawlader, M.D.H. (2018) Descriptive Epidemiology of Multidrug Resistance Tuberculosis (MDR-TB) in Bangladesh. Journal of Tuberculosis Research, 6, 292-301. doi: 10.4236/jtr.2018.64026.