Author(s)

Aurélien Ndoumbe^1*, Mathieu Motah¹, Bea Jesse Ikango¹, Mireille Moumi², Amadou Fewou³, Albert Mouelle Sone¹

¹Faculty of Medicine & Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
²Neurosurgeon, Service of Surgery, General Hospital of Douala, Douala, Cameroon.
³Pathology, Faculty of Medicine & Biomedical Sciences, University of Yaoundé I. Head, Service of Pathology, General Hospital of Douala, Douala, Cameroon.

The diagnosis and management of cerebral gliomas are challenging. The goal of this study was to evaluate the pattern of cerebral gliomas at the General Hospital Douala, Cameroon. A retrospective study was carried out over a period of 10 years. Non-glial lesions were not included. Data were analyzed with Epi info version 7.2.2.6 (Microsoft, Seattle, USA). 220 cases of brain tumors, comprising 56 gliomas (25.46% of all brain tumors) were managed during the study period. The mean age of the patients was 42.93 ± 16.90 years. 35 cases (62.5%) were males. Patients over 15 years of age represented 91.07% (n = 51) of the cases. The most frequent presenting complaints were headache and vomiting with 52 cases (92.86%) and 47 cases (83.93%) respectively. Brain computed tomography was done for all patients. The most frequent histological type was astrocytoma with 22 cases (39.29%) followed by glioblastoma with 20 cases (35.71%). The most performed surgical technique was partial removal with 33 cases (58.93%), followed by open biopsy with 14 cases (25.00%). Radiotherapy was administered to 54 patients (96.43%). The outcome ranged from full recovery in 8 cases (14.29%), recovery with persisting symptoms, in 15 cases (26.79%) and death in 26 cases (46.43%). Seven patients (12.50%) were lost to view. In this series, cerebral gliomas affected most often adult males. Most of them presented with signs of raised intracranial pressure. The outcome was poor with 46.43% of patients dying before 2 years after diagnosis.

Cerebral Gliomas, Clinical Manifestations, Histological Nature, Management, Outcome

Ndoumbe, A. , Motah, M. , Ikango, B. , Moumi, M. , Fewou, A. and Sone, A. (2018) Cerebral Gliomas Patterns at the General Hospital of Douala, Cameroon. Open Journal of Modern Neurosurgery, 8, 389-405. doi: 10.4236/ojmn.2018.84035.