Author(s)

Yonghao You¹, Rongting Liu^2*

¹Department of Surgery, Clinical Medical College of Yangtze University, Jingzhou, China.
²Department of Gastrointestinal Surgery, First People’s Hospital of Jingzhou, Jingzhou, China.

Objective: The efficacy of Ji Desheng snake pills combined with hypertonic glucose external application in treating drug-induced superficial phlebitis caused by parenteral nutrition (PN) is observed. Methods: Fifty-two cases of drug-induced superficial phlebitis after peripheral parenteral nutrition (PPN) were selected, which were randomly divided into experimental group and control group in accordance with the phlebitis grading. In the experimental group, Ji Desheng snake pills were crushed to make a paste with 50% glucose solution, which was then applied to the affected area of phlebitis, the surface was covered with clean gauze, and properly fixed with tape or bandage. The drug was replaced once a day. In the control group, the gauze soaked with 50% magnesium sulfate solution was used, which was applied to the affected part three times a day in wet, and the efficacy was observed respectively on the 1^st, 3^rd, 5^th and 7^th days after applying the drug. Results: On the 1^st and 3^rd days after treatment, the observed effective rate of the experimental group was higher than that of the control group (42.31% vs. 15.38% and 76.92% vs. 46.15%, respectively). The difference was statistically significant (p < 0.05). In terms of the effective rate observed on the 5^th and 7^th days after treatment, there was no statistical significance with respect to the efficacy between the experimental group and the control group (p > 0.05). Conclusion: The significant efficacy could be found in early stage after drug-induced superficial phlebitis was treated by Ji Desheng snake pills combined with hypertonic glucose external application, which was superior to that of the traditional treatment of wet application by using gauze soaked in 50% magnesium sulfate solution.

Ji Desheng Snake Pills, Hypertonic Glucose, Parenteral Nutrition, Drug-Induced Superficial Phlebitis

You, Y. and Liu, R. (2018) Application of Ji Desheng Snake Pills Combined with Hypertonic Glucose External Application in Treating Drug-Induced Superficial Phlebitis Caused by Parenteral Nutrition. Yangtze Medicine, 2, 108-113. doi: 10.4236/ym.2018.22012.