This study provides an overview of the level of ability of autonomous regions of Natuna Regency-Riau Islands Province on the border of Indonesia, to design the formation of new autonomous regions based on the criteria of regional formation referring to GR. 129 of 2000/No. 78 of 2007, and the Draft Government Regulation on Area Arrangement. This study uses the application of measurement model and evaluation of the ability of a region in the implementation of regional autonomy, so the sample is a saturated sample, where the population consists of 15 districts, 70 villages and 6 sub-urban. This research concludes that the division in Natuna can be designed in 4 alternatives that can become its own province, if the Anambas Islands Regency, which is the division of Natuna Regency also plan the establishment of 1 new autonomous region (NAR), so the requirement for the manufacture of special province, South China Sea waters can be achieved because Natuna will be divided into 3 (three) autonomous regions while the Anambas Islands District will be divided into 2 (two) autonomous regions. 5 (five) autonomous regions shall be the basic requirement for the establishment of 1 (one) autonomous region at the provincial level.