Author(s)

Demid Oyuntsetseg¹, Оchirpurev Мunkhjargal¹, Chimed Mandalshaihan¹, Avirmed Amgalanbaatar², Enebish Sundui², Hany Wahila¹, Amgalanbaatar Dorjkhuu²

¹Department of Professional Science, Gobi-Altai School of Mongolian National University of Medical Sciences, Gobi-Altai, Mongolia.
²Morphology Department, Bio-Medicine and Pharmacology School of Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia.

Studies have shown that autoimmunity causes pathogenesis of more than 100 diseases. Among these diseases, approximately 1-2% of the world’s population has rheumatoid arthritis disease, which is a chronic disease that affects 45 out of every 3000 people who have autoimmune diseases. The aim of this research is to address the possible treatment of rheumatoid arthritis disease by comparing and contrasting the effectiveness and influence that treatments have on treating the disease. This study will be conducted by inducing the following treatments: ibuprofen and Boigor-10 on model animal subjects (mice) to determine the outcomes of the treatment. We will assess the outcomes by investigate the structural changes on vertebrae and joints of these subjects and the clinical manifestation score of each treatment. We hypothesize that these treatments will improve the treatment of rheumatoid arthritis disease. Furthermore, we hope that this research contributes to further understanding autoimmune disease and promotes proper treatment of the disease.

Arthritis, Joint, Experiment, Pannus, Vertebra, Histology

Oyuntsetseg, D., Мunkhjargal, О., Mandalshaihan, C., Amgalanbaatar, A., Sundui, E., Wahila, H. and Dorjkhuu, A. (2018) Structural Changes in Vertebrae of Mice Based on Experimental Model of Rheumatoid Arthritis. Open Journal of Applied Sciences, 8, 1-11. doi: 10.4236/ojapps.2018.81001.