Diagnosing and Managing Androgen Insensitivity Syndrome

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DOI: 10.4236/oju.2017.711026    860 Downloads   2,195 Views  

ABSTRACT

Introduction: Androgen insensitivity syndrome is a rare congenital abnormality of genital organs revealing a female phenotype in a person with XY chromosomes. The aim of our work is to describe the clinical aspects, to determine the chromosomal sex and to report our therapeutic management. Observation: A 28-year-old woman with female phenotype, feminine voice, normal breast development, normal underarms and pubic hair, absence of menstruation, fusion of small and large vaginal lips leaving a small pertuis to serve as urethral meatus. On the dorsal surface of the large, left lip was a mass the size of a date. Hormonal balance was normal. A feminizing genitoplasty was performed as well as excision of the mass. Histological analysis of the mass concluded that it was a feminizing testicular. Conclusion: Androgen insensitivity syndrome is a rare abnormality of the genitals. Multidisciplinary management is essential both for the designation of the breeding sex and feminizing genitoplasty.

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Rimtebaye, K. , Mpah, E. , Kamadjou, C. , Tashkand, A. , Sillong, F. , Kaboro, M. , Niang, L. and Gueye, S. (2017) Diagnosing and Managing Androgen Insensitivity Syndrome. Open Journal of Urology, 7, 219-225. doi: 10.4236/oju.2017.711026.

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