Author(s)

Jesus Reyna-Figueroa^1*, Irina Jeanette Bercholc-Urinowsky¹, Gabriela Cardoso-Yah¹, Ricardo Platón Vazquez-Alvarado¹, Dalila Ramos-López¹, Freya Helena Campos-Romero¹, Cory Handelsman², Ana Elena Limón-Rojas¹

¹Central South Hospital, Mexican Oil Company, Petróleos Mexicanos, México City, Mexico.
²Robert Wood Johnson University Hospital, New Jersey, USA.

Introduction: Mild and moderate Adverse Events Following Immunization (AEFI) against Rotavirus has not received much attention when the vaccine is administered regardless of recommended age restriction. Objectives: To describe the behavior of mild and moderate AEFI in immunized subjects against Rotavirus, in who age restriction period had not been considered. Methods: A case-control study in which we included immunized patients with monovalent oral vaccine against rotavirus and divided them into two groups: 1) Infants who received RV1 vaccine without considering the recommended period, and 2) Infants who were vaccinated with the recommended schedule. Results: From the total doses, 143/1894 (7.5%) were administered outside the restriction period. The most frequent AEFIs with the first dose were purpura, polypnea, and rhinorrhea; For the second dose: purpura, bloody stools, irritability and rhinorrhea. Conclusions: This study shows the benefits from vaccination regardless of age restriction are more beneficial compared to the possible risks of AEFI.

Rotavirus, Vaccination, Age Restriction, Adverse Reaction

Reyna-Figueroa, J. , Bercholc-Urinowsky, I. , Cardoso-Yah, G. , Vazquez-Alvarado, R. , Ramos-López, D. , Campos-Romero, F. , Handelsman, C. and Limón-Rojas, A. (2017) Evaluation of Adverse Events Following Immunization against Rotavirus Regardless of Recommended Age Restriction. Journal of Biosciences and Medicines, 5, 78-82. doi: 10.4236/jbm.2017.58006.