Author(s)

Hiromitsu Yamamoto¹, Ken-Ichiro Murakami², Mariko Kawai^1,3, Hitoshi Nagatsuka⁴, Kazuhisa Bessho¹

¹Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
²Department of Oral and Maxillofacial Surgery, Ako City Hospital, Ako, Japan.
³Department of Pharmacology, Osaka Dental University, Osaka, Japan.
⁴Department of Oral Pathology and Medicine, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan.

Ameloblastoma is an odontogenic tumor of high frequency and usually occurs as an intraosseous growth. Ameloblastomas frequently recur, sometimes undergoing malignant transformation. These tumors are usually characterized as being multilocular, of the follicular type histopathologically, and invading strongly at the border region of the tumor. More than 10% p53-positive tumor cells give a prognostic indication for a tendency to recur. A recurrent ameloblastoma usually occurs in the intraosseous region near the site of the original lesion. In very rare cases, a recurrent tumor proliferates distantly from the original site in the soft tissue only. We report a rare case of recurrent ameloblastoma in the buccal mucosa with a mucocele that originated from the small salivary glands after the extirpation of an intraosseous (mandibular) ameloblastoma. We also performed a p53 immunohistochemical study of this recurrent tumor.

Ameloblastoma, Soft Tissue Recurrence, Follicular Type, Mucocele, p53

Yamamoto, H. , Murakami, K. , Kawai, M. , Nagatsuka, H. and Bessho, K. (2017) Soft Tissue Recurrence with a Mucocele of an Intraosseous Ameloblastoma. Open Journal of Stomatology, 7, 336-344. doi: 10.4236/ojst.2017.78028.