Author(s)

Comlan Jules Gninkoun¹, Adébayo Sabi Cossi Alassani², Yempabou Sagna³, Philippe Adjagba⁴, François Djrolo¹

¹Department of Internal Medicine-Endocrinology, Metabolism and Nutrition Unit, Cotonou, Benin.
²University Hospital of Borgou, Parakou, Benin.
³Department of Internal Medicine, University Hospital Yalgado Ouedraogo, Ougadougou, Burkina Faso.
⁴Cardiology and Vascular Disease Unit, Cotonou, Benin.

We performed a retrospective study on diabetic ketosis decompensations in 101 diabetic patients in Endocrinology and Metabolic Diseases Service of the National Hospital and Universitary Koutoukou Hubert Maga (CNHU-HKM) for a period of 3 years. Objective: The main objective of the study was to identify the underlying factors of ketosis decompensations for a more focused education program. Results: The mean age was 43.84 years. In half of cases (49.5%), the ketosis decompensations were inaugural for the diabetes. Type 2 diabetes was predominant with a frequency of 85.1% versus 14.9% for type 1 diabetes. The overall prevalence rate of ketosis decompensations was 21.82%. The precipitating factors were infections (51.49%) and treatment withdrawal (25.74%). The average blood glucose was 4.46 g/L with ranges of 1.86 g/L and 13 g/L. The outcome was favorable in 89.1% of cases. The mortality rate was 7.9%. The average hospital stay was 13.23 days. Conclusion: This study showed that ketosis decompensations are still frequent. The main precipitating factors are infection and therapeutic noncompliance. Preventive actions are needed through screening programs, regular monitoring and targeted education.

Ketoacidosis, Diabetes, Complications, Ketosis-Prone

Gninkoun, C. , Alassani, A. , Sagna, Y. , Adjagba, P. and Djrolo, F. (2016) Diabetic Ketosis Decompensations at the National Hospital in Benin (West Africa), What Did We Learn about the Precipitating Factors?. Journal of Diabetes Mellitus, 6, 301-306. doi: 10.4236/jdm.2016.64031.