Antibacterial Activity of Pterocarpus osun L. on Multi-Drug Resistant (MDR) Escherichia coli from Wound Infections in Abeokuta, South-West Nigeria - Open Access Library Journal

OALibJ > Vol.2 No.8, August 2015

Antibacterial Activity of Pterocarpus osun L. on Multi-Drug Resistant (MDR) Escherichia coli from Wound Infections in Abeokuta, South-West Nigeria ()

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DOI: 10.4236/oalib.1101434 1,044 Downloads 2,477 Views Citations

Author(s)

Bode Ireti Shobayo¹, David Ajiboye Ojo¹, David Adejare Agboola²

Affiliation(s)

¹Department of Microbiology, Federal University of Agriculture, Abeokuta, Nigeria.
²Department of Biology, Federal University of Agriculture, Abeokuta, Nigeria.

ABSTRACT

Pterocarpus osun plant has been used overtime in the indigenous system of medicine. In this study, methanol, ethanol and aqueous extracts of leaves of P. osun were examined against five Escherichia coli strains obtained from wounds. Antibacterial effect of the plant leaves, in the concentration of 100 mg/ml, was determined using disc diffusion method. Phytochemical screening of extracts of the leaves revealed the presence of phenols, flavonoids, tannins, terpenoids alkaloids, and glycosides. Leaves extracts of P. osun showed different zones of inhibition to the Escherichia coli isolates in the different solvents used. Results from this study showed that extracts of P.osun had broad spectrum of activity on the tested bacteria.

KEYWORDS

Pterocarpus osun L., Antibacterial Activity, Multi-Drug Resistance, Wound

Share and Cite:

Shobayo, B. , Ojo, D. and Agboola, D. (2015) Antibacterial Activity of Pterocarpus osun L. on Multi-Drug Resistant (MDR) Escherichia coli from Wound Infections in Abeokuta, South-West Nigeria. Open Access Library Journal, 2, 1-6. doi: 10.4236/oalib.1101434.

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