Prevalence of Herpes Simplex Virus in Pregnant Women from Gangetic Plain Region of Allahabad, India - Advances in Microbiology

AiM > Vol.5 No.6, June 2015

Prevalence of Herpes Simplex Virus in Pregnant Women from Gangetic Plain Region of Allahabad, India ()

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DOI: 10.4236/aim.2015.56041 3,652 Downloads 5,499 Views Citations

Author(s)

Omar Ahmed Omar Amar^1,2, Harish Kumar Bajaj¹, Neena Gupta¹, Ankit Singla², Harison Masih^2*

Affiliation(s)

¹Medical Technology Laboratory, Sam Higginbottom Institute of Agriculture, Technology and Sciences, Allahabad, India.
²Department of Microbiology and Fermentation Technology, Sam Higginbottom Institute of Agriculture, Technology and Sciences, Allahabad, India.

ABSTRACT

Herpes Simplex Virus (HSV) is a common pathogen that leads to lifelong latent infection and may be associated with transmission from mother to their fetus. A total of 191 blood samples of pregnant women were collected to check the prevalence of Herpes Simplex Virus (HSV). It was observed that 124 (64.9%) and 04 (2.1%) samples were positive for HSV IgG and HSV IgM, respectively. Seropositivity of HSV IgG was the highest for third trimester and it was followed by second and first trimester; while it was the highest for first trimester for HSV IgM and it was followed by third and second trimester. Seroprevalence of HSV IgG and IgM was statistically insignificant (P > 0.05) according to gestation age. A significant correlation was observed between HSV IgG and age groups of pregnant women; while it was insignificant for HSV IgM. Seroprevalence of HSV IgG⁺ IgM^- was 32 (53.3%), 61 (66.3%), and 27 (69.2%) for first, second and third trimester, respectively. Seroprevalence of HSV IgG⁺ IgM⁺ group was 02 (3.3%), 01 (1.1%) and 01 (2.6%) for first, second and third trimester, respectively. Seroprevalence of HSV IgG^- IgM^- group was 26 (43.3%), 30 (32.6%), and 11 (28.2%) for first, second and third trimester, respectively.

KEYWORDS

Herpes Simplex Virus, Seroprevalence, IgG, IgM, Quantitative ELISA

Share and Cite:

Amar, O. , Bajaj, H. , Gupta, N. , Singla, A. and Masih, H. (2015) Prevalence of Herpes Simplex Virus in Pregnant Women from Gangetic Plain Region of Allahabad, India. Advances in Microbiology, 5, 404-408. doi: 10.4236/aim.2015.56041.

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