Author(s)

Victoria Tamara Perchyonok¹, Vanessa Reher², Nicolaas J. Basson³, Shengmiao Zhang⁴, Sias R. Grobler³

¹VTPCHEM PTY LTD, Gold Coast, Australia.
²School of Dentistry and Oral Health, Griffith University, Gold Coast, Australia.
³Oral and Dental Research Institute, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa.
⁴School of Material Science and Engineering, East China University of Science and Technology, Shanghai, China.

In this work, Bioactive-functionalized interpenetrating network (IPNs) hydrogel (BIOF-INPs) were prepared and investigated in vitro for the free radical detection/defense, therapeutic release as well as shear bond strength to dentine, ability to re-mineralize surface of the dentin after application of these bio-inspired materials using a biologically inspired mineralization process in vitro as well as investigating antimicrobial properties of the BIOF-INPs against S. aureous. The aim of this investigation was to evaluate the suitability and flexibility of the designer materials to act as an “in vitro” probe to gain insights into molecular origin of TMD and associated disorders.

TMD, Functionalized IPNs, Bio-Adhesion, Drug Release, Build in Free Radical Detection and Defense

Perchyonok, V. , Reher, V. , Basson, N. , Zhang, S. and Grobler, S. (2015) Bioinspired-Interpenetrating Network (IPNs) Hydrogel (BIOF-INPs) and TMD in Vitro: Bioadhesion, Drug Release and Build in Free Radical Detection and Defense. Open Journal of Stomatology, 5, 53-61. doi: 10.4236/ojst.2015.53008.