Effect of Non-Delineated Normal Volumes in IMRT Treatment for Left Breast Cancer: A Treatment Planning Study - International Journal of Medical Physics, Clinical Engineering and Radiation Oncology

IJMPCERO > Vol.4 No.1, February 2015

Effect of Non-Delineated Normal Volumes in IMRT Treatment for Left Breast Cancer: A Treatment Planning Study ()

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DOI: 10.4236/ijmpcero.2015.41003 4,441 Downloads 5,867 Views

Author(s)

Tamer Dawod¹, Sabbah I. Hammoury^2*, Mostafa Elnaggar³, Mustafa Kamal⁴

Affiliation(s)

¹Clinical Oncology and Nuclear Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
²Medical Physics Department, Alexandria Ayadi Almostakbl Oncology Center (AAAOC), Alexandria, Egypt.
³Department of Cancer Management and Research Medical Research Institute, Alexandria University, Alexandria, Egypt.
⁴Metal Physics Lab, Physics Department, Faculty of Science, Mansoura University, Mansoura, Egypt.

ABSTRACT

Introduction: Intensity Modulated Radiation Therapy (IMRT) planning dose calculation process depends on IMRT dose constraints. So, if there was any structure along the treatment beam path not delineated, it would not be taken into account during that calculation process. During IMRT routine practical work, it is noticed that there are some non-delineated normal tissue volumes that received un-aimed dose. Aim: The purpose of this study was to study the effect of unusually delineated normal volumes in IMRT treatment for left sided breast cancer. Method: Ten left sided breast cancer patients were planned with IMRT inverse planning system. The unusually delineated normal volumes were delineated and taken into account in IMRT dose constraints as an Organ at Risk. Doses received by that volume were compared in the two methods quantitatively from Dose Volume Histograms (DVHs) and qualitatively from (axial cuts). Results: The results showed that doses received by the unusually delineated volume when they were delineated and taken into account in IMRT dose constraints were significantly higher than when they were not. Conclusions: The results showed that for IMRT planning technique used for treating left-sided breast cancer, all of the normal tissues/structures that are closed to the treatment targets must be delineated and taken into account in the IMRT planning dose constraints.

KEYWORDS

Radiotherapy, IMRT, Linear Accelerator, Treatment Planning System TPS, NTIAV

Share and Cite:

Dawod, T. , Hammoury, S. , Elnaggar, M. and Kamal, M. (2015) Effect of Non-Delineated Normal Volumes in IMRT Treatment for Left Breast Cancer: A Treatment Planning Study. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, 4, 13-24. doi: 10.4236/ijmpcero.2015.41003.

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