Author(s)

Santosh Kumar Yadav

Department of Organic Chemistry & FDW, Andhra University, Visakhapatnam, India.

Vilsmeier reagent formed from phthaloyl dichloride and DMF was found to be very effective for converting 2-hydroxyacetophenones, deoxybenzoins and dihydrochalcones into corresponding chromones, isoflavones and homoisoflavones with excellent yield. This method offers significant advantages such as efficiency and mild reaction conditions with shorter reaction time.

Phthaloyl Dichloride, Dimethylformamide, Chromones, Isoflavones, Homoisoflavones, BF3·Et2O, Vilsmeier Reagent

Yadav, S. (2014) Process for the Preparation of Chromones, Isoflavones and Homoisoflavones Using Vilsmeier Reagent Generated from Phthaloyl Dichloride and DMF. International Journal of Organic Chemistry, 4, 236-246. doi: 10.4236/ijoc.2014.44027.