The equivalent stress at key positions of Bogie Frame for DMUs Exported to Tunisia is obtained by using simulation analysis. The evaluation of static strength and fatigue strength is checked referring to UIC specification and Goodman sketch for welding materials. In addition, the modal analysis of the frame is made, and the vibrational modal of frame in given frequency domain is predetermined to evaluate the dynamical behavior of the frame in order to meet the dynamical design requirements. The results show that the key points of the calculated frame of the equivalent stress are less than allowable stress, and thus it could provide a theoretical foundation for the optimized design of frame structure and safety of industrial production.