Author(s)

Ihsane Souaf, Kawtar Znati, Sanae Chahbouni, Imane Hafid, Hassania Ameurtesse, Nawale Hammas, Leila Chbani, Hinde El Fatemi, Tawfik Harmouch, Afaf Amarti

Department of Pathology, Hassan II University Hospital of Fez, Hassan, Morocco.

Introduction: Signet ring cell carcinoma is a rare tumor that generally originates in the gastrointestinal tract. Signet-ring cell carcinoma of the ampulla of Vater is extremely uncommon and a very rare clinical entity, which is infrequently reported in medical literature and only 31 cases have been mentioned. Most tumors affecting Vater’s Ampulla are adenocarcinomas and other histological variants are less frequent. It mainly occurs in elderly patients. Case Presentation: We report a case of signet ring cell carcinoma of Vater’s Ampulla. The tumour had infiltrated the duodenal, but local lymph nodes were clear (T3N0M0). Duodenopancreatectomy with pylorus preservation is the treatment of choice. Conclusions: Etiology and survival are not well-defined in the literature due to the extreme rarity of this disease.

Ampulla of Vater; Carcinoma; Signet Ring Cell; Pancreas

Souaf, I. , Znati, K. , Chahbouni, S. , Hafid, I. , Ameurtesse, H. , Hammas, N. , Chbani, L. , Fatemi, H. , Harmouch, T. and Amarti, A. (2014) Signet Ring Cell Carcinoma of Ampulla of Vater: Report of a Rare Malignancy and Literature Review. Case Reports in Clinical Medicine, 3, 145-148. doi: 10.4236/crcm.2014.33035.