The article is devoted to analysis of the atmosphere and soil pollution’s monitoring and health status of the Krasnodar region city’s population (the South of the Russian Federation). Studies were conducted during more than 20 years, and there was repeated testing of the soil in various regions and cities. The results indicate an increase of the atmosphere pollution and of the concentrations of chemical elements in soil and deterioration of health of the population as a consequence. Especially the children and adult population with diseases of the respiratory tract strongly increased. The population medical records studies are based on the health research and the atmosphere and the soil chemical analysis results in the pollution monitoring. Ni, Cr, Cu and Pb concentrations in the region soils increased during the observation period. The highest degree of air pollution in southern Russia was marked in Novorossiysk.