We present a photometric investigation in the uvbyβ system of a 20° × 20° field centered at galactic coordinates (l, b) = (105°, 5°). This region contains a relatively isolated structure of numerous HII regions in the direction of some of the OB associations in Cepheus and Cassiopeia. Photoelectric uvbyβ data of more than 220 stars of spectral types O-B9 are available for this field and are used to obtain homogeneous distance estimates for a number of prominent stellar groups, among which are the Cep OB2 and Cep OB3 associations and the open clusters NGC 7243 and NGC 7654.