Synthesis, Characterization, Anti-Bacterial and Anti-Fungal Activities of New Quinoxaline 1,4-di-N-Oxide Derivatives

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DOI: 10.4236/ijoc.2013.33A007    4,895 Downloads   7,556 Views  Citations

ABSTRACT

A new series of quinoxaline 1,4-di-N-oxides were synthesized and evaluated for their antibacterial and antifungal activities. The best result was demonstrated by 3-amino-N-(4-methoxyphenyl)-2-quinoxalinecarboxamide 1,4-di-N-oxide 4e, MIC (0.24 μg/ml) against Aspergillus fumigatus, and (0.12 μg/ml) against Streptococcus pneumonia.

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D. Soliman, "Synthesis, Characterization, Anti-Bacterial and Anti-Fungal Activities of New Quinoxaline 1,4-di-N-Oxide Derivatives," International Journal of Organic Chemistry, Vol. 3 No. 3A, 2013, pp. 65-72. doi: 10.4236/ijoc.2013.33A007.

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