Share This Article:

Diphenyl methane laxatives do not induce electrolyte imbalance

Full-Text HTML Download Download as PDF (Size:106KB) PP. 272-275
DOI: 10.4236/ojgas.2013.35046    4,542 Downloads   6,183 Views

ABSTRACT

Aim: To analyse whether there are changes in sodium and potassium serum levels during chronic treatment with the diphenyl methanes bisacodyl and sodium picosulfate. Methods: A literature search was done using PubMed, and the reference lists of pertinent papers were screened for additional studies. Only studies of at least 4 weeks duration were considered for further analysis. Results: Four relevant studies were identified. In three randomised controlled trials with 5 to 10 mg daily of bisacodyl or sodium picosulfate, respectively, over four weeks no electrolyte losses were found. Hypokalemia was also not a problem in a group of patients with paraplegia using bisacodyl suppositories for 2 to 34 years. Conclusions: Electrolyte losses, particularly hypokalemia, are not a problem when bisacodyl or sodium picosulfate are used long-term.

Cite this paper

Müller-Lissner, S. (2013) Diphenyl methane laxatives do not induce electrolyte imbalance. Open Journal of Gastroenterology, 3, 272-275. doi: 10.4236/ojgas.2013.35046.

Copyright © 2019 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.