Author(s)

Tuan A. Tran, Jeremy O’Connor, Xavier Fagan, Tu Tran, Dan Nguyen

Department of Glaucoma, Victorian Eye and Ear Hospital, Melbourne, Australia;.
Department of Medical Ophthalmology, Victorian Eye and Ear Hospital, Melbourne, Australia..
Department of Politecnico Ophthalmology, Sydney Eye Hospital, Sydney, Australia;.

Necrotizing scleritis is the most severe form of scleritis with a significant threat to vision and globe integrity. It can be infectious, surgically induced necrotizing scleritis (SINS) or systemic autoimmune associated. We report a case of necrotizing scleritis associated with 5-fluorouracil (5-FU) at the site of sub tenon’s block in a patient with previous trabeculectomy. To our knowledge, this is the first reported case of necrotizing scleritis associated with 5-FU. This may implicate alternative approaches to local anaesthetic techniques when using adjunctive 5-FU.

Necrotizing Scleritis; 5-Fluorouracil; Sub-Tenon’s Block; Glaucoma

Tran, T. , O’Connor, J. , Fagan, X. , Tran, T. and Nguyen, D. (2013) Necrotizing Scleritis Associated with 5-Fluorouracil and Sub-Tenon’s Block in Patient with Previous Trabeculectomy: A Case Report. Open Journal of Ophthalmology, 3, 73-75. doi: 10.4236/ojoph.2013.33018.