Author(s)

Sara Terenzi, Daniela di Cristino, Alessandra Murgia, Dania Janniello, Elisabetta Ponti, Barbara Tolu, Sara Cicchetti, Riccardo Santoni

Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology and Radiotherapy, Tor Vergata University General Hospital, Rome, Italy..

Purpose: To report a retro-orbital localization of Multiple Myeloma (MM) describing its treatment and clinical result. Case report: A 50-years-old male patient with Magnetic Resonance Imaging (MRI) evidence of a retro-orbital mass with exophthalmos, due to the pathological diagnosis of MM, was referred for Radiation Therapy (RT). Discussion: The orbital involvement in Multiple Myeloma is rare and few cases are reported in the literature. The treatment of choice is RT alone with a prescribed dose ranging between 40 Gy and 45 Gy. In our patient the retro-orbital lesion, measuring 26 × 16 mm, was treated with Intensity Modulated Radiotherapy Technique (IMRT) delivering 4400 cGy with conventional fractionation. The treatment was well tolerated, the patient experienced a complete regression of the exophthalmos without any significant side effect.

Plasma Cell Tumours; Multiple Myeloma; Tumours of the Orbit; Radiation Therapy

S. Terenzi, D. Cristino, A. Murgia, D. Janniello, E. Ponti, B. Tolu, S. Cicchetti and R. Santoni, "Orbital Involvement in Multiple Myeloma: A Case Report," Journal of Cancer Therapy, Vol. 3 No. 6, 2012, pp. 1052-1054. doi: 10.4236/jct.2012.36136.