Author(s)

Sergio Clementi, Mauro Fernandi, Massimo Baroni, Diego Decastri, Giuseppe Marco Randazzo, Fabrizio Scialpi

Flint Group, Cinisello Balsamo, Milano, Italy.
Laboratory for Chemometrics and Cheminformatics, Chemistry Department, University of Perugia, Perugia, Italy.
M.I.A. Multivariate Infometric Analysis Srl, Perugia, Italy.
Molecular Discovery Ltd., London, England.

The paper illustrates an innovative procedure for experimental design in mixture analysis. It relies on D-optimal designs performed on the combinatorial explosion of five levels of components composition, keeping in mind the requirements of Central Composite Designs. The final response surface model is obtained by the formerly developed CARSO method.

Mixture Analysis; Optimization; Design Strategies; CARSO Procedure

S. Clementi, M. Fernandi, M. Baroni, D. Decastri, G. Randazzo and F. Scialpi, "Mauro: A Novel Strategy for Optimizing Mixture Properties," Applied Mathematics, Vol. 3 No. 10A, 2012, pp. 1260-1264. doi: 10.4236/am.2012.330182.