Author(s)

Fable Zustovich, Mario Trivellato, Renato Ceravolo, Davide Pastorelli, Rosanna Canton, Lorena Buratin, Monica Mion, Martina Zaninotto, Martina Mattiazzi, Mario Plebani, Giuseppe Cartei

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Chemotherapy induced cardio-toxicity is a well known side effect of anticancer treatments, moreover the 70% of all tumors involve patients over 65 years-old, frequently with cardiac co- morbidity. We evaluated the feasibility of the application during chemotherapy administration of some of the most recent diagnostic techniques as 12-diagnostic leads telemetry, 7 days EKG monitoring device (R-Test Evolution 3R), blood level dosage of Brain Natriuretic Peptide (BNP) and Ischemia Modified Albumin (IMA). Some sub-clinical changes in the investigated parameters were found in patients undergoing chemotherapy, mostly containing fluorouracil, as shown in the following paper. Far from suggesting a widespread use of these methods during chemotherapy administration, we think that some more tools are needed to prevent cardiac toxicity in high-risk patients and some of what we studied may deserve further valuation in chemotherapy clinical trials.

Cardio-Toxicity Diagnostic

Zustovich, F. , Trivellato, M. , Ceravolo, R. , Pastorelli, D. , Canton, R. , Buratin, L. , Mion, M. , Zaninotto, M. , Mattiazzi, M. , Plebani, M. and Cartei, G. (2010) Cardio-Toxicity during chemotherapy: feasibility of new diagnostic approaches. Health, 2, 376-380. doi: 10.4236/health.2010.24056.