The role of fine-wire localization breast biopsy in the management of BI-RADS category 3-5 non-palpable breast lesions in northeastern Chinese women

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DOI: 10.4236/health.2010.24042    5,919 Downloads   10,503 Views  Citations

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ABSTRACT

A blinded retrospective validation study was performed in a university-based hospital in northeastern China to determine whether the breast imaging reporting and data system (BI- RADS) defines a group of patients with non- palpable breast lesions (NPBLs) in whom fine- wire localization biopsy (FWLB) is appropriate. We reviewed 182 consecutive patients with NPBLs who underwent FWLB. The patients’ preoperative mammograms were categorized according BI-RADS by 2 radiologists blinded to the pathological findings. The positive predictive values of BI-RADS categories 3-5 were 3.4%, 42.1%, and 76.9%, respectively. For category 4 NPBLs, the percentage of cancer for those aged < 40 years was significantly lower than those aged ≥ 40 years. For category 3 NPBLs, the percentage of precancerous lesions for those aged < 40 years was significantly lower than those aged ≥ 40 years. Chinese NPBL patients aged ≥ 40 years with category 4 mammographic findings, and all patients with category 5 findings should undergo FWLB. FWLB should be offered as a treatment option for Chinese NPBL patients aged < 40 years with category 4 findings or aged ≥ 40 years with category 3 findings.

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Chen, B. , Liu, C. , Jin, F. , Sun, Y. , Zhao, T. , Zhang, L. , Li, S. and Yeung, S. (2010) The role of fine-wire localization breast biopsy in the management of BI-RADS category 3-5 non-palpable breast lesions in northeastern Chinese women. Health, 2, 291-294. doi: 10.4236/health.2010.24042.

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