Dr. Adriana C. Vidal

Department of Obstetrics and Gynecology

Division of Clinical and Epidemiological Research

Duke University School of Medicine, USA

Email: adriana.vidal@duke.edu

Qualifications

1991 Ph.D., Department of Biology, Pharmacy and Biochemistry, Universidad Nacional del Sur, Bahia Blanca, Buenos Aires, Argentina

1984 B. S., Biology, Department of Biology, Pharmacy and Biochemistry Universidad Nacional del Sur, Bahia Blanca, Buenos Aires, Argentina

Publications (Selected)

1. Vidal, A. C., Murtha, A.P., Murphy, S.K., Overcash, F., Schildkraut, J.M., Forman, M., Demark-Wahnefried, W.,  Kurtzberg, J, Jirtle, R., and Hoyo, C. Associations between antibiotic exposure during pregnancy, birth weight, and aberrant methylation at imprinted genes among offspring.  International Journal of Obesity 2013; doi:10.1038/ijo.2013.47.
2. Vidal, A. C., Henry, N. M., Murphy, S., Overcash, F., Oneko, O., Nye, M., Swai, B., Vasquez, B., Hernandez, B. Y., Obure, J., Mlay, P., Bartlett, J., Overcash, F., Huang, Z., Wang, F.,  Smith, J., and Hoyo, C. MEST/PEG1 and IGF2 methylation in CIN and in cervical cancer (2013). Clinical and Translational Oncology, in press.
3. Vidal, A. C., Murtha, A.P., Murphy, S.K., Overcash, F., Henry, N., Schildkraut, J.M., Forman, M., Demark-Wahnefried, W.,  Kurtzberg, J, Jirtle, R., and Hoyo, C. Maternal BMI, IGF-I levels and birth weight in African American and White infants.  International Journal of Pediatrics, vol. 2013, Article ID 191472, 2013. doi:10.1155/2013/191472.
4. Nye, M., Hoyo, C., Huang, Z., Vidal, A. C., Wang, F., Overcash, F., Vasquez, B., Hernandez, B. Y., Swai, B., Oneko O., Obure, J., Mlay, P., Bartlett, J. A., and Murphy, S. K. Associations between methylation of Paternally Expressed Gene 3, cervical intraepithelial neoplasia and invasive cervical cancer in Tanzania. PloS ONE 2013;8:e56325.
5. Vidal, A. C., Grant, D., Williams, C., Shuler K, Calloway, E., Gerber, L., Masko, E., Allot, E., Freedland, S. and Hoyo, C. Associations between intake of folate, vitamins B-12, B-6 and prostate cancer risk in American Veterans. Journal of Cancer Epidemiology 2012;2012:957467.
6. Vidal, A. C., Keku, T., Hoyo, C., Simmons, J., Galanko, J., Burcal, L., Holston, R., Massa, B., Omofoye, S., Sandler, R., and Lund, P.K. Elevated C-peptide and reduced IGFBP-1 predicts risk of colorectal adenomas in normal mucosa. BMC Cancer 2012;12:389.
7. Hoyo, C., Murphy, S.K., Schildkraut, J.M., Vidal, A. C., Skaar, D., Millikan, R.C., Galanko, J., Sandler, R.S., Jirtle, R., and Keku, T. IGR2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites. Disease Markers 2012;32:133-141.
8. Keku,  T.O., Vidal, A. C., Hoyo, C., Oliver, S., Hall, I.J., Omofoye, S., McDoom, M., Worley, K., Galanko, J., Sandler, R.S., and Millikan, R. Insulin-pathway related gene polymorphisms, influence on plasma levels and associations with colon cancer in African Americans and Whites. Cancer Causes and Control 2012;23:1127-1138.
9. Vidal, A. C., Murphy, S. K., Hernandez, B. Y., Vazquez, B., Bartlett, J. A., Oneko, O., Overcash, F., Smith, J., van der Kolk, M., and Hoyo, C. Distribution of HPV genotypes in cervical intraepithelial lesions and cervical cancer in Tanzanian women. Infectious Agents and Cancer 2011;6:20.
10. Tong, J., Briggs, M.M., Mlaver, D., Vidal, A.C., and McIntosh, TJ. Sorting of lens aquaporins and connexins into raft and nonraft bilayers: Role of protein homo-oligomerization. Biophysical Journal 2009;97:2493-2502.
11. Tong, J., Nguyen, L., Vidal, A. C., Simon S.A., Skene, P.J.H., and McIntosh, T.J. Role of GAP-43 in sequestering phosphatidylinositol 4,5-bisphosphate (PIP2) to raft bilayers. Biophysical Journal 2008; 94:125-133.
12. Vidal, A. C. and McIntosh, T.J. Transbilayer peptide sorting between raft and non-raft bilayers: Comparisons of detergent extraction and confocal microscopy. Biophysical Journal 2005;89: 1102-1108.
13. Allende, D., Vidal, A. C., and McIntosh, T.J. Jumping to rafts: Gatekeeper role of bilayer elasticity. Trends in Biochemical Sciences 2004;29: 325-330.
14. McIntosh, T.J., Vidal A. C., and Simon, S.A. Sorting of lipids and transmembrane peptides between detergent-soluble bilayers and detergent-resistant rafts. Biophysical Journal 2003;85: 1656-1666.
15. Allende, D., Vidal, A. C., Simon, S.A., and McIntosh T.J. Bilayer interfacial properties modulate the binding of amphipathic peptides. Chemistry and Physics of Lipids 2003;122:65-76.
16. Gandhavadi M., Allende, D., Vidal, A. C., S.A. Simon, and T.J. McIntosh. Structure, composition, and peptide binding properties of detergent soluble bilayers and detergent resistant rafts. Biophysical Journal 2002;82:1469-1482.
17. McIntosh, T.J., Vidal A. C., and Simon, S.A. The energetics of binding of a signal peptide to lipid bilayers: role of bilayer properties. Biochem Soc Trans 2001;29 (4) 594-598.
18. Dawson, J.R., Vidal, A. C., and Malyguine A.M. Natural killer cell-endothelial cell interactions in xenotransplantation. Immunologic Research 2001;22/2-3:165-176.
19. Vidal, A. C., Prado Figueroa, M., Eberwein, M.E., Kreda, S. and Barrantes, F. J. Co-distribution of tropomyosin and -actinin with actin in Psammobatis extenta electrocytes brings out their similarity with muscle fiber cytoplasm. Comp Biochem Physiol 1997;116A: 113-118.
20. Prado Figueroa, M., Vidal, A. C., and Barrantes, F. J. Ultrastructure of Psammobatis extenta (Rajidae) electrocytes and cytochemical localization of acetylcholinesterase, acetylcholine receptor and F-actin. BIOCELL 1995;19(2): 113-123.
21. Kramarcy, N., Vidal, A. C., Froehner, S.C. and Sealock, R. Association of utrophin and multiple dystrophin short forms with the mammalian Mr 58,000 dystrophin-associated protein (syntrophin).  J Biol Chem 1994; 269: 2870-2876.
22. Marcheselli, V., Daniotti, J.L., Vidal, A.C., Maccioni, H., Marsh, D. and Barrantes, F.J.  Gangliosides in acetylcholine receptor-rich membranes from Torpedo marmorata and Dyscopygetschudii. Neurochem Res 1993;18: 599-603.