Biography

Dr. D. James Morré
Purdue Research Park, USA

Laboratory Director


Email: prunck@yahoo.com


Qualifications

1963 Biochemistry, California Institute of Technology, USA

1959 Plant Physiology, Purdue University, USA

1957 Science, University of Missouri, USA


Publications

(Selected)


  1. Chueh, P.-J., Kim, C., Cho, N. M., Morré, D. M. and Morré, D. J. 2002. Molecular cloning and characterization of a tumor-associated and growth-related time keeping hydroquinone (NADH) oxidase of the HeLa cell surface. Biochemistry 41: 3732-3741.
  2. Chueh, P.-J., Wu, L.-Y., Morré, D. M. and Morré, D. J.   2004. tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (_)-epigallocatechin-3-gallate. BioFactors 20: 249-263.
  3. Morré, D. J., Chueh, P.-J., Yagiz, K., Balicki, A., Kim, C. and Morré, D. M. 2007. ECTO-NOX target for the anticancer isoflavene phenoxodiol. Oncology. Res. 16: 299-312.
  4. Tang, X., Tian, Z., Chueh, P.-J., Chen, S., Morré, D. M. and Morré, D. J. 2007. Alternative splicing as the basis for specific localization of tNOX, a unique hydroquinone (NADH) oxidase, to the cancer cell surface. Biochemistry 46: 12,337-12,346.
  5. 5.   Tang, X., Morré, D. J. and Morré, D. M. 2008. Antisense experiment demonstrate cancer-specific   encoding of functional tNOX through an exon 4 minus splice variant. Oncology Res. 16: 557-567.
  6. Geng, L., Rachakonda, G., Morré, D. J., Morré, D. M., Crooks, P. A., Sonar, V. N., Roti Roti, J. L., Rogers, B., Greco, S., Ye, F., Salleng, K., Freeman, M. L. and Sekhar, K. R. 2009. Indolyl-quinuclidinois inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vaculature. FASEB J. 23: 2986-2995.
  7. Hostetler, B., Weston, N., Kim, C, Morré, D. M. and Morré, D. J. 2009. Cancer site-specific isoforms of ENOX2 (tNOX), a cancer-specific cell surface oxidase. Clin. Proteomics 5: 46-51.
  8. Morré, D. J., Geilen, C. C., Welch, A. M. and Morré, D. M. 2009. Response of carcinoma in situ (actinic keratosis) to green tea concentrate plusCapsicum. J. Dietary Suppl. 6: 385-389.
  9. Morré, D. J., Morré, D. M. and Brightmore, R. 2010. Omega-3 but not omega-6 unsaturated fatty acids inhibit the cancer-specific ENOX2 of the HeLa cell surface with no effect on the constitutive ENOX1. J. Dietary Suppl. 7: 154-158.98.
  10. De Luca, T., Morré, D. M. and Morré, D. J. 2010. Reciprocal relationship between cytosolic NADH and ENOX2 inhibition triggers sphingolipid-induced apoptosis in HeLa cells. J. Cell. Biochem. 11: 1504-1511.109.
  11. De Luca, T., Bosneaga E., Morré, D. M. and Morré, D. J. 2009. Downstream targets of altered sphingolipid metabolism in response to inhibition of ENOX2 by phenoxodiol. BioFactors 34: 253-260.
  12. Tang, X., Kane, V. D., Morré, D. M. and Morré, D. J. 2011. hnRNP F directs formation of an exon 4 minus variant of tumor associated NADH oxidase (ENOX2). Mol. Cell. Biochem. 357: 55-63.
  13. Wu, L.-Y., De Luca, T., Watanabe, T., Morré, D. M. and Morré, D. J. 2011. Metabolite modulation of HeLa cell response to ENOX2 inhibitors EGCg and phenoxodiol. Biochim. Biophys. Acta 1810: 784-789.
  14. Morré, D. J. and Morré, D. M. 2012. Early detection: an opportunity for cancer prevention through early intervention. In: Cancer Prevention, Georgakilas, A. G. (ed.). InTech, Vienna, pp. 389-402.
  15. Morré, D. J. and Morré, D. M. 2012.   ECTO-NOX proteins. Springer, New York, 507 pp.


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