Prof. Chi-Yu Gregory Lee

University of British Columbia, Canada

Professor Emeritus

Email: cyglee@yahoo.com

Qualifications

1972 Post-doctoral Fellow, Department of Chemistry, University of California, USA

1972 Ph.D., Department of Chemistry, California Institute of Technology, USA

1971 M.Sc., Department of Chemistry, California Institute of Technology, USA

Publications (Selected)

Journals

1. G. Lee, M. Zhu, B. Ge, S. Potzold, (2012), Widespread expressions of immunoglobulin superfamily proteins in cancer cells, Cancer Immunology Immunotherapy, 61: 89-99.
2. G. Lee, B. Li, Y. Li, Y. Wang, M. Zhu, B. Ge, S. Potzold, B. Giolma, Z. Chen, (2012), CA215 and GnRH Receptor as Targets for Cancer Therapy, 61: 1805-1817.
3. G. Lee, B. Li, B. Ge, P-M. Chow, (2012), Molecular and Immuno-Characteristics of Immunoglobulin-like Glycoproteins in Cancer Cell-expressed Biomarker, CA215, Immunological Investigations, 41: 429-446.
4. G. Lee, P. Azadi, (2012), Peptide mapping and glycoanalysis of cancer cell-expressed glycoproteins, CA215 recognized by RP215 monoclonal antibody, Journal of Carbohydrate Chemistry, 31: 1, 10-30.
5. G. Lee, M. Zhu, B. Ge, (2012), Potential monoclonal antibody therapy for the treatment of ovarian cancer. InTech-Open Access Publisher “Ovarian Cancer- Basic Science Perspective” Book I (ISBN 978-953-307-812-0), Ed. Samir Farghaly Chapter 19, p385-406.
6. G. Lee, M. Zhu, B. Ge, A. P. Cheung, C. H. Chien, S. N. Chow, Y. P. Ding and H. X. Yao, (2012), Carbohydrate-associated Immunodominant Epitope(s) of CA215. Immunol Invest, 41: 317-36.
7. M. Zhu, B. Ge, S. Potzold, Z. Yao, B. Giolma, G. Lee, (2011), Widespread expressions of immunoglobulin superfamily proteins in cancer cells, Cancer Immunology and Immunotherapy, 61: 89-99.
8. G. Lee, A. Cheung, B. Ge, M. Zhu, P. Li, E. Hsu, T-K, Huang, (2010),Monoclonal anti-idiotype antibodies against carbohydrate-associated epitope-based for anti-cancer vaccine development. J Vaccin. Vaccin. 1, 106: doi:10.4172/2157-7560.1000106.
9. G. Lee, B. Ge, T-K, Huang, X Zheng, J Duan, IHY Wang, (2010), Positive identification of CA215 Pan cancer biomarker from serum specimens of cancer patients. Cancer Biomarkers 6: 111-117.
10. G. Lee, B. Ge, (2010), Inhibition of in vitro tumor cell growth by RP215 monoclonal antibody and antibodies raised against its anti-idiotypic antibodies. Cancer Immunology and Immunotherapy 59: 1347-1356.
11. G. Lee, B. Ge, (2010), Growth inhibition of tumor cells in vitro by using monoclonal antibodies against gonadotroin-releasing hormone receptor. Cancer Immunol Immunother. 59: 1011-1019.
12. Gregory Lee, Rui-Ai Chu and Hong Hoi Ting, (2009), Preclinical assessment of anti-cancer drugs by using RP215 monoclonal antibody, Cancer Biology & Therapy, 8:2, 161-166.
13. G. Lee, (2009) Cancer cell-expressed immunoglobulins: CA215 as a pan cancer marker and its diagnostic applications, Cancer Biomarkers, 5: 137-142.
14. G. Lee and B. Ge, (2009), Cancer cell expressions of immunoglobulin heavy chains with unique carbohydrate-associated biomarker, Cancer Biomarkers, 5: 177–188.
15. G.Lee, (2009), Cancer cell-expressed immunoglobulins, CA215 as a pan cancer marker and its diagnostic applications, Cancer Biomarkers, 5: 137-142.
16. G. Lee, R.-A. Chu, H. H. Ting. (2009), Preclinical assessment of anti-cancer drugs by using RP215 monoclonal antibody, 8: 19-24.
17. G. Lee, E. Laflamme, C-G. Chien, H. H. Ting. (2008), Molecular Identity of A Pan Cancer Marker, CA215. Cancer Biology & Therapy, 7: 2007-2014.
18. Lee, H. Tsao, P. Lam, J. Fan. (2007), Comparative Clinical Evaluations of Rapid Immunoassay Tests of Fatty Acid Binding Protein and Three other Cardiac Markers.  J. Clin. Ligand Assay 29: 1-5.
19. Lee G., Wu Q., Li C.H., Ting H. H. and Chien C.-H., (2006) Recent studies of a new carbonhydrate-associated pan cancer marker, CA215, Journal of Clinical Ligand Assay, 29: 1-6.
20. T. Taketo, C-H Lee, J. Zhang, Y. Li, C.Y.G. Less and Y-F C. Lau. (2005), “Expression of SRY proteins in both normal and sex-reversed XY fetal mouse gonads” Develop Dynamics.

Books

1. Lee, C.Y.G. and Liu, M.S. (1990), Biochemical and immunological responses of sperm antigens and immunocontraception.   In Advances in Reproductive Health Care (E.S.E. Hafez, ed.) Vol. VI, pp. 51-80.
2. Lee, C.Y.G., Liu, M.S., Su, M.W. and Zhu, J.B. (1990), Studies of sperm antigens reactive to HS-11 and HS-63 monoclonal antibodies.  In Gamete Interaction: Prospect for Immunocontraception (Alexander, N.J., Griffin D, eds.) Wiley-Liss Inc. pp. 37 - 52.
3. Rowe, T.C. and Lee, C.-Y G. (1988), Application of Intrauterine Insemination. in Ratnam, S.S., Teoh, E.-S and Ng, S.-C. (eds.) In Vitro Fertilization and other Alternative Methods of Conception, Advances in Fertility and Sterility Series, Vol. 2, IFFS Publishers, Singapore, pp. 133-136.
4. Lee, C.Y. G., Y.S. Moon, A. Duleba, A. F. Chen and V. Gomel. (1985) Gossypol Inhibition of LDH-X. In Lobl, T.J. and E.S.E. Hafez (eds.), Male Fertility and Its Regulation - Advances in Reproductive Health Care, MTP Press, pp. 193-199.
5. Lee, C.Y.G., Y.S. Moon, A. Duleba, A. F. Chen, J.H. Yuan and V. Gomel. (1985), Gossyypol: A Potential Male Contraceptive.  In Segal, S. (ed.), Biochemical Studies of Gossypol, Plenum Press, New York, London, pp. 237 - 244.
6. Menge, A.C., D.E. Richter, R.K. Naz, C. Y. G. Lee and E. Wong. (1983), Dissecting the Sperm Cell by Use of Monoclonal Antibodies. In Isojima, S. and W.D. Billington (eds.), Reproductive Immunology, Amsterdam: Elsevier Science Publishers, pp. 81 - 90.
7. Lee, C. Y. G. and A. F. Chen., (1982), Immobilized Coenzymes and Derivatives.  In Everse, J., K.-S. You and B.M. Anderson (eds.), Pyridine Nucleotide Coenzymes, Chapter 6, Academic Press, New York, pp. 189-224.
8. Lee, C. Y. G., J. H. Yuan and E. Goldberg., (1982), Lactate Dehydrogenase Isozymes from Mouse.  In Wood, W.A. (ed.), Methods in Enzymology Carbohydrate Metabolism, Academic Press, New York, Vol. 89, pp. 251-258.
9. Lee, C.Y.G. (1982), 3-Phophoglycerate Kinase Isozymes and Genetic Variants from Mouse.  In Wood, W.A. (ed.), Methods in Enzymology-Carbohydrate Metabolism, Academic Press, New York, Vol. 90, pp. 121-126.
10. Lee, C.Y.G. (1982), Multiple Forms of Hexokinase in Drosophila Melanogaster.  In Wood, W.A. (ed.), Methods in Enzymology-Carbohydrate Metabolism, Academic Press, New York, Vol. 90, pp. 16 – 21.
11. Lee, C.Y.G. (1982), Sn-glycerol-3-phospate Dehydrogenase from Drosophila Melanogaster.  In Wood, W.A. (ed.), Methods in Enzymology-Carbohydrate Metabolism, Academic Press, New York, Vol 89, pp. 242-247.
12. Lee, C.Y.G. (1982), Glucose-6-phosphate Dehydrogenase from Mouse.  In Wood, W.A. (ed.), Methods in Enzymology-Carbohydrate Metabolism, Academic Press, Vol. 89, pp. 242-247.
13. Lee, C.Y.G. (1982), Phosphoglucose Isomerase from Mouse and Drosophila Melanogaster.  In Wood, W.A. (ed.), Enzymology-Carbohydrate Metabolism, Academic Press, New York, Vol. 89, pp. 559-562.
14. Yang Y. Y., Yoshiki, T., Lee, Y. T. and Lee, C. Y. G. Anti-trophoblast monoclonal antibodies for prenatal genetic diagnosis. in Fetal cells in maternal blood Vol. 731. (Simpson, J.L., Elias, S., eds.)  Prospect for Non-invasive Prenatal Diagnosis. Annals of New York Academy of Sciences. pp. 178 - 180.