Biography

Dr. Wayne R. Hogrefe

Clinical Trials Program, USA


Email: whogrefe@focusdx.com


Qualifications


1979 Ph.D., Case Western Reserve University, Experimental Pathology

1972 B.T., University of Dayton, Chemical Technology


Publications (selected)

  1. Catanzaro, P.J., Graham, R.C., and Hogrefe, W.R.: Mouse Peritoneal Lymphocytes: A Morphological Comparison of Normal and Exudate Peritoneal Cells. J. Reticuloendothel. Soc. 16: 161, 1974.
  2. Catanzaro, P.J., Brandt, W.E., Hogrefe, W.R. and Russell, P. K.: Detection of Dengue Cell surface Antigens by Peroxidase-Labelled Antibodies and Immune Cytolysis, Infect. Immun. 10: 381, 1974.
  3. Catanzaro P.J., Brandt, W.E., Hogrefe, W.R., Phillips, S.M. and top, F.E.: Virus Enhanced Modulation of Cell Surface Antigens: Effect on Immune Lytic Susceptibility, J. Immunol. 117: 1104, 1976.
  4. Hogrefe, W.R., Agniel, L.D., Catanzaro, P.J., and Phillips, S.M.: Interaction of Peritoneal Exudate Lymphocytes with Histocompatibility Antigens, Cell. Immunol. 29: 394, 1977
  5. Laqui, C., Hogrefe, W.R., Askari, A., Laipply, T.C. and Rassiga, A.: Sjogren's Syndrome with IgA/Kappa Immunoglobulinemia and Acute Lymphocytic Lymphoma, Lymphoplasmacytic Variant. Arch Inter Med 145:935, 1985.
  6. Elias, J., la Nebe, V., Beutner, E., Hogrefe, W. et al., Optimal Conditions for Demonstrating Human Lymphocyte Differentiation Antigens. A working Protocol for the Immunohistochemical Analysis of a Lymph Node Biopsy. J. Histotech 8: 201,1985.
  7. Kumar, A, Gena, R, Kulkarmi, R, Hogrefe, W, and Kaufman, D, Immunogloublins in Hemophilia: Correlation Between IgG Subclasses, IgE and HIV Antibody. J. Clin. Lab. Immunol 31:157-160, 1990.
  8. Leigner, K., Shagine, J., Ramsey, D., Halperin, A., Hogrefe, W. and Kong, L.,Recurrent Erythema Chronicum Migrans Despite Extended Antibiotic Treatment in a Patient with Persisting B.burgdorferi Infection, Confirmed by Polymerase Chain Reaction (PCR) assay. J. Amer. Acad. Derm 28:312-314,1993.
  9. Murray, J.C., Kelley, B.A., Hogrefe, W.R., and McClain, K.L., Childhood Idiopathic Thrombocytopenia Purpura: Association with Human Parvovirus B19 Infection. J. Ped. Hematol/Oncol. 16(4):314-319, 1994.
  10. Norman, G.L., Antig, J.M., Bigaignon, G., Hogrefe, W.R., Serodiagnosis of Lyme Borreliosis by B. burgdorferi sensu strict, B. garinii and B. afzelii Western Blots. J. Clin. Microbiol. 34:1732-1738, 1996.
  11. Lohiya, G.S., Hogrefe, W.R., Tan-Figueroa, L., Caires, S., Parvovirus B19-Antibody Serosurvey in 500 Developmentally Disabled Subjects. Infection Control and Hosp Epidem, 18:340, 1997.
  12. Prince, N.E. and Hogrefe, W.R., Evaluation of a Line Immunoblot Assay for Detection of Antibodies Recognizing Extractable Nuclear Antigens. J. Clin. Lab Analysis 12:320, 1998.
  13. Laferl, H., Hogrefe, W., Kock, T., Pichler, H.: A Further Case of Acute Human Granulocytic Ehrlichiosis in Slovenia. Eur. J. Clin. Microbiol. Infect. Dis. 18:385-386, 1999.
  14. Garcia-Corbiera, P., Hogrefe, W., Aguilar, L., Garcia-Det Lomas, J. Gil, A.,Bayas, J.M., Vilella, A., Dal-Re, R., Whole Cell Lysate Enzyme Immunoassays vs. Recombinant Glycoprotein G2-Based Immunoassays for HSV-2 Seroprevalance Studies. J Med Virol 59:502-506, 1999.
  15. Prince, H., Ernst, C., Hogrefe, W. Evaluation of An Enzyme Immunoassay System For Measuring Herpes Simplex Virus (HSV) Type 1 - Specific And HSV Type 2 - Specific IgG Antibodies. J. Clin. Labor. Anal. 14:13-16, 2000.
  16. Olano, J., Hogrefe, W., Seaton, B., Walker, D.H. Clinical Manifestations, Epidemiology, and Laboratory Diagnosis of Human Monocytotropic Ehrlichiosis in a Commercial Laboratory Setting. Vector-Borne Dis. J. 2002.
  17. Hogrefe, W., Su, X., Song, J., Ashley, R., Kong, L. The Detection of HSV2 IgG Antibodies in African Sera Using Recombinant gG2, Western Blot, and gG2 Inhibition. J. Clin. Microbiol. 40:3635-3640, 2002.
  18. Hogrefe, W., Ernst, C., Su, X. Efficiency of IgG Reconstitution from Dried Blood Filter specimens and Utility in HSV Type-Specific Serology Screening. Clin. Diagn. Lab. Immunol. 9: 1338 – 1342, 2002
  19. Smith, H., Reporter, R., Rood, M., Linscott, A., Mascola, L., Hogrefe, W., Purcell, R. Prevalence Study of Antibody to Ratborne Pathogens and Other Agents Among Patients using a Free Clinic in Downtown Los Angeles. J. Infect. Dis. 186:1673 – 1676, 2002
  20. Prince, H., Hogrefe, W. Performance Characteristics of an In-house West Nile Virus (WNV) IgM Assay System During the 2001 WNV Season in the United States. Clin. Diagn. Lab. Immunol. 10:177 – 179, 2003
  21. Olano, J., Hogrefe, W., Seaton, B., Walker, D. Clinical Manifestations, Epidemiology, and Laboratory Diagnosis of Human Monocytotropic Ehrlichiosis in a Commercial Laboratory Setting. Clin. Diagn. Lab. Immunol. 10: 891 – 896, 2003
  22. Prince, H., Hogrefe, W. Detection of West Nile Virus (WNV)-Specific Immunoglobulin M in a Reference Laboratory Setting during the 2002 WNV Season in the United States. Clin. Diagn. Lab. Immunol. 10: 764 – 768, 2003
  23. Olano, J., Masters, E., Hogrefe, W., Walker, D. Human Monocytic Ehrlichiosis, Missouri. Emerging Infectious Diseases. 9: 1579 – 1586, 2003
  24. Prince, H., Lape-Nixon, M., Moore, R., Hogrefe, W. Utility of the Focus Technologies West Nile Virus Immunoglobulin M Capture Enzyme-Liked Immunosorbent Assay for Testing Cerebrospinal Fluid. J. Clin. Microbiol. 42:12 – 15, 2004
  25. Laeyendecker, O., Henson, C., Gray, R., Nguyen, R., Horne, B., Wawer, M., Serwadda, D., Kiwanuka, N., Ashley-Morrow, R., Hogrefe, W., Quinn, T.Performance of a Commercial, Type-Specific Enzyme-Linked Immunosorbent Assay for the Detection of Herpes Simples Virus Type 2-Specific Antibodies in Ugandans. J. Clin. Microbiol. 42: 1794-1796, 2004

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