Dr. Wayne R. Hogrefe
Clinical Trials Program, USA
Email: whogrefe@focusdx.com
Qualifications
1979 Ph.D., Case Western Reserve University, Experimental Pathology
1972 B.T., University of Dayton, Chemical Technology
Publications (selected)
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Catanzaro, P.J., Graham, R.C., and Hogrefe, W.R.: Mouse Peritoneal Lymphocytes: A Morphological Comparison of Normal and Exudate Peritoneal Cells. J. Reticuloendothel. Soc. 16: 161, 1974.
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Catanzaro, P.J., Brandt, W.E., Hogrefe, W.R. and Russell, P. K.: Detection of Dengue Cell surface Antigens by Peroxidase-Labelled Antibodies and Immune Cytolysis, Infect. Immun. 10: 381, 1974.
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Catanzaro P.J., Brandt, W.E., Hogrefe, W.R., Phillips, S.M. and top, F.E.: Virus Enhanced Modulation of Cell Surface Antigens: Effect on Immune Lytic Susceptibility, J. Immunol. 117: 1104, 1976.
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Hogrefe, W.R., Agniel, L.D., Catanzaro, P.J., and Phillips, S.M.: Interaction of Peritoneal Exudate Lymphocytes with Histocompatibility Antigens, Cell. Immunol. 29: 394, 1977
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Laqui, C., Hogrefe, W.R., Askari, A., Laipply, T.C. and Rassiga, A.: Sjogren's Syndrome with IgA/Kappa Immunoglobulinemia and Acute Lymphocytic Lymphoma, Lymphoplasmacytic Variant. Arch Inter Med 145:935, 1985.
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Elias, J., la Nebe, V., Beutner, E., Hogrefe, W. et al., Optimal Conditions for Demonstrating Human Lymphocyte Differentiation Antigens. A working Protocol for the Immunohistochemical Analysis of a Lymph Node Biopsy. J. Histotech 8: 201,1985.
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Kumar, A, Gena, R, Kulkarmi, R, Hogrefe, W, and Kaufman, D, Immunogloublins in Hemophilia: Correlation Between IgG Subclasses, IgE and HIV Antibody. J. Clin. Lab. Immunol 31:157-160, 1990.
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Leigner, K., Shagine, J., Ramsey, D., Halperin, A., Hogrefe, W. and Kong, L.,Recurrent Erythema Chronicum Migrans Despite Extended Antibiotic Treatment in a Patient with Persisting B.burgdorferi Infection, Confirmed by Polymerase Chain Reaction (PCR) assay. J. Amer. Acad. Derm 28:312-314,1993.
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Murray, J.C., Kelley, B.A., Hogrefe, W.R., and McClain, K.L., Childhood Idiopathic Thrombocytopenia Purpura: Association with Human Parvovirus B19 Infection. J. Ped. Hematol/Oncol. 16(4):314-319, 1994.
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Norman, G.L., Antig, J.M., Bigaignon, G., Hogrefe, W.R., Serodiagnosis of Lyme Borreliosis by B. burgdorferi sensu strict, B. garinii and B. afzelii Western Blots. J. Clin. Microbiol. 34:1732-1738, 1996.
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Lohiya, G.S., Hogrefe, W.R., Tan-Figueroa, L., Caires, S., Parvovirus B19-Antibody Serosurvey in 500 Developmentally Disabled Subjects. Infection Control and Hosp Epidem, 18:340, 1997.
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Prince, N.E. and Hogrefe, W.R., Evaluation of a Line Immunoblot Assay for Detection of Antibodies Recognizing Extractable Nuclear Antigens. J. Clin. Lab Analysis 12:320, 1998.
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Laferl, H., Hogrefe, W., Kock, T., Pichler, H.: A Further Case of Acute Human Granulocytic Ehrlichiosis in Slovenia. Eur. J. Clin. Microbiol. Infect. Dis. 18:385-386, 1999.
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Garcia-Corbiera, P., Hogrefe, W., Aguilar, L., Garcia-Det Lomas, J. Gil, A.,Bayas, J.M., Vilella, A., Dal-Re, R., Whole Cell Lysate Enzyme Immunoassays vs. Recombinant Glycoprotein G2-Based Immunoassays for HSV-2 Seroprevalance Studies. J Med Virol 59:502-506, 1999.
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Prince, H., Ernst, C., Hogrefe, W. Evaluation of An Enzyme Immunoassay System For Measuring Herpes Simplex Virus (HSV) Type 1 - Specific And HSV Type 2 - Specific IgG Antibodies. J. Clin. Labor. Anal. 14:13-16, 2000.
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Olano, J., Hogrefe, W., Seaton, B., Walker, D.H. Clinical Manifestations, Epidemiology, and Laboratory Diagnosis of Human Monocytotropic Ehrlichiosis in a Commercial Laboratory Setting. Vector-Borne Dis. J. 2002.
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Hogrefe, W., Su, X., Song, J., Ashley, R., Kong, L. The Detection of HSV2 IgG Antibodies in African Sera Using Recombinant gG2, Western Blot, and gG2 Inhibition. J. Clin. Microbiol. 40:3635-3640, 2002.
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Hogrefe, W., Ernst, C., Su, X. Efficiency of IgG Reconstitution from Dried Blood Filter specimens and Utility in HSV Type-Specific Serology Screening. Clin. Diagn. Lab. Immunol. 9: 1338 – 1342, 2002
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Smith, H., Reporter, R., Rood, M., Linscott, A., Mascola, L., Hogrefe, W., Purcell, R. Prevalence Study of Antibody to Ratborne Pathogens and Other Agents Among Patients using a Free Clinic in Downtown Los Angeles. J. Infect. Dis. 186:1673 – 1676, 2002
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Prince, H., Hogrefe, W. Performance Characteristics of an In-house West Nile Virus (WNV) IgM Assay System During the 2001 WNV Season in the United States. Clin. Diagn. Lab. Immunol. 10:177 – 179, 2003
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Olano, J., Hogrefe, W., Seaton, B., Walker, D. Clinical Manifestations, Epidemiology, and Laboratory Diagnosis of Human Monocytotropic Ehrlichiosis in a Commercial Laboratory Setting. Clin. Diagn. Lab. Immunol. 10: 891 – 896, 2003
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Prince, H., Hogrefe, W. Detection of West Nile Virus (WNV)-Specific Immunoglobulin M in a Reference Laboratory Setting during the 2002 WNV Season in the United States. Clin. Diagn. Lab. Immunol. 10: 764 – 768, 2003
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Olano, J., Masters, E., Hogrefe, W., Walker, D. Human Monocytic Ehrlichiosis, Missouri. Emerging Infectious Diseases. 9: 1579 – 1586, 2003
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Prince, H., Lape-Nixon, M., Moore, R., Hogrefe, W. Utility of the Focus Technologies West Nile Virus Immunoglobulin M Capture Enzyme-Liked Immunosorbent Assay for Testing Cerebrospinal Fluid. J. Clin. Microbiol. 42:12 – 15, 2004
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Laeyendecker, O., Henson, C., Gray, R., Nguyen, R., Horne, B., Wawer, M., Serwadda, D., Kiwanuka, N., Ashley-Morrow, R., Hogrefe, W., Quinn, T.Performance of a Commercial, Type-Specific Enzyme-Linked Immunosorbent Assay for the Detection of Herpes Simples Virus Type 2-Specific Antibodies in Ugandans. J. Clin. Microbiol. 42: 1794-1796, 2004
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