Prof. Maria Grigoroiu-Serbanescu

Alexandru Obregia Psychiatric Hospital, Romania

Email: maria.serbanescu@googlemail.com

Qualifications

1982 Ph. D., at the University of Bucharest

Publications (Selected)

1.     T.W. Mühleisen, M. Leber, T. G. Schulze, J Strohmaier, F. Degenhardt, J. Treutlein, M. Mattheisen, R. Breuer, S Meier, S Herms, P. Hoffmann, A. Lacour, A Reif, B. Müller-Myhsok, S. Lucae, W. Maier, M. Schwarz, H. Vedder, J Kammerer-Ciernoch, J. Sasse, M. Bauer, M. Hautzinger, S. Moebus, L. Priebe, P.M. Czerski, J. Hauser, J. Lissowska, N. Szeszenia-Dabrowska, IARC/CNG GWAS Initiative, A. Wright, P.B. Mitchell, J.M. Fullerton, P.R. Schofield, G.W. Montgomery, S.E. Medland, S.D. Gordon, N.G. Martin, A. Chuchalin, G. Babadjanova, G. Pantelejeva, L.I. Abramova, A. S Tiganov, A. Polonikov, E. Khusnutdinova, M. Alda, P. Grof, G. A. Rouleau, G. Turecki, D. Daley, C. Laprise, F. Rivas, F. Mayoral, M. Kogevinas, M. Grigoroiu-Serbanescu, P. Propping, T. Becker, M. Rietschel, M,M. Nöthen, S. Cichon. Genome-wide association study reveals two new risk loci for bipolar disorder. Nature Communications, 2014. Accepted. IF = 10.01.

2.     Manchia M, Adli M, R. Ardau, J-M Aubry, L. Backlund, C. E.M. Banzato, B. Baune, F. Bellivier, J. M. Biernacka, C. Brichant-Petitjean, E. Bui, A.Tai Ann Cheng, C. Chillotti, Sven Cichon, P. Czerski, C. Dantas, M. Del Zompo,, J. R. DePaulo, S. D. Detera-Wadleigh, B. Etain, P. Falkai, L. Frisén, M. A. Frye, J. Fullerton, J. Garnham, F. S. Goes, P. Grof, O. Gruber, R. Hashimoto, J. Hauser, U. Heilbronner, R. Hoban, L. Huo, N. Iwata, S. Jamain, L. Kassem, T. Kato, J. R. Kelsoe, S. Kittel-Schneider, S. Kliwicki, P-H Kuo, I. Kusumi, G. Laje, C. Lavebratt, M. Leboyer, S. G. Leckband, C. A. López Jaramillo, M. Maj, Alain Malafosse, L. Martinsson, T. Masui, P. Mitchell, F. Mondimore, P. Monteleone, T. Novák, U. Ösby, N. Ozaki, R. H. Perlis, A. Pfennig, J. B. Potash, D. Reich-Erkelenz, A. Reif, E. Reininghaus, S. Richardson, G. A. Rouleau, J. K. Rybakowski, M. Schalling, P. R. Schofield, B. Schweizer, F. Seemüller, M. Grigoroiu-Serbanescu, G. Severino, L.R. Seymore, C. Slaney, J. W. Smoller, A. Squassina, T. Stamm, Jo Steele, P. Stopkova, S. Tighe, A. Tortorella, G. Turecki, N. Wray, A. Wright, T. Yoshikawa, P. Zandi, M. Bauer, M. Rietschel, F. J. McMahon, T. G. Schulze, M. Alda. Assessment of response to lithium maintenance treatment in bipolar disorder: a Consortium on Lithium Genetics (ConLiGen) report. PLoS One, 2013, 8: (6), Article Number: e65636. IF = 4,09.

3.     Vassos E, Steinberg S, Cichon S, Breen G, Sigurdsson E, Andreassen OA, Djurovic S, Morken G, Grigoroiu-Serbanescu M,  Diaconu CC, Czerski PM,  Hauser J, Babadjanova G, Abramova L, Mühleisen TW, Nöthen MM, Rietschel M, McGuffin P, St Clair D, Gustafsson O, Melle I, Pietiläinen OPH, Ruggeri M, Tosato S, Werge T, Ophoff RA, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I, Rujescu D, Børglum AD, Mors O, Mortensen PB, Demontis D, Hollegaard MV, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Rubino AI, Golimbet V, Kiemeney LA, van den Berg LH, Franke B, Jönsson EG, Farmer A, Stefansson H, Stefansson K, Collier DA. Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder. Biological Psychiatry, 2012, 72 (8): 645-650, IF = 9,24.

4.     Grigoroiu-Serbanescu M, Wickramaratne PJ, Mihailescu R, Prelipceanu D, Sima D, Codreanu M, Grimberg M, Elston RC. Paternal age effect on age of onset in bipolar I disorder is mediated by sex and family history. American Journal of Medical Genetics (B) – Neuropsychiatric Genetics, 2012, 159B, 567-579, IF = 3,23.

5.     C Hammer, S Cichon, T W Muehleisen, B Haenisch, F Degenhardt, M Mattheisen, R Breuer, S H Witt, J Strohmaier, L Oruc, F Rivas, G Babadjanova, M Grigoroiu-Serbanescu, J Hauser, R Roeth, G Rappold, M Rietschel, M M Noethen, B Niesler. Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study. Translational Psychiatry (Nature Publishing Group) 2012, 2: e-pub, e103.

6.     L Priebe, F Degenhardt, S Herms, B Haenisch, M Mattheisen, V Nieratschker, M Weingarten, S Witt, R Breuer, T Paul, M Alblas, S Moebus, M Lathrop, M Leboyer, S Schreiber, M. Grigoroiu-Serbanescu, W Maier, P Propping, M Rietschel, MM Nöthen, S Cichon, TW Mühleisen. Genome-wide survey implicates the influence of copy number variants (CNVs) on the development of early-onset bipolar disorder, Molecular Psychiatry (Nature Publishing Goup), 2012, 17:421-432, IF = 14,89.

7.     Cichon S, Mühleisen TW, Degenhardt F, Mattheisen M, Miró X, Strohmaier J, Steffens M, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, Schmael C, Tessmann P,Moebus S, Wichmann EH, Schreiber S, Müller-Myhsok B, Lucae S, Muglia P, Jamain S, Leboyer M, Heath S, Kapur-Pojskic L, Oruc L, Rivas F, Mayoral F, Babadjanova G, Grigoroiu-Serbanescu M,Diaconu CC, Czerski PM, Hauser J, Zimmer A, Lathrop M, Schulze TG, Wienker TF, Schumacher J, Maier W, Propping P, Rietschel M, Nöthen MM . Genome-wide association study identifies a novel susceptibility gene for bipolar disorder and schizophrenia: neurocan (NCAN). American Journal of Human Genetics, 88 (3): 372-381. IF=11,68.

8.     Grigoroiu-Serbanescu M, Herms S, Diaconu CC, Abou Jamra R, Meier S, Bleotu C , Neagu AI, Prelipceanu D, Sima D, Gherghel M, Mihailescu R , Rietschel M, Nöthen MM, Cichon S, Mühleisen TW. Possible association of different g72/g30 SNPs with mood episodes and persecutory delusions in bipolar I Romanian patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 34, 2010,657–663, IF = 3,55.

9.     Grigoroiu-Serbanescu M, Herms S , Georgi A, Diaconu CC , Strohmaier J , Czerski P , Hauser J , Leszczynska-Rodziewicz A , Vollmer J , Rami Abou Jamra R, Babadjanova G, Tiganov A, Krasnov V ,Kapiletti S , Neagu AI, Mühleisen TW , Breuer R , Rietschel MM, Nöthen MM, Cichon S. Variation in P2RX7 candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples. American Journal of Medical Genetics – Neuropsychiatric Genetics, Vol. 150B, ( 7), 2009, 1017-1021. IF = 3,23.

10.   Steinhausen HC, Grigoroiu-Serbanescu M, Boyadjieva S, Neumärker KJ, Metzke CW. The relevance of body weight in the medium-term to long-term course of adolescent anorexia nervosa. Findings from a multisite study. International Journal of Eating Disorders, 2009; 42(1):19-25. IF = 2,87.

11.   Grigoroiu-Serbanescu M, Diaconu CC , Herms S, Bleotu C, Prelipceanu D, Mühleisen TW, Vollmer J, Mihailescu R, Georgescu MJ, Sima D, Grimberg M, Nöthen MM, Cichon S (2008), Investigation of the tryptophan hydroxylase 2 (TPH2) gene in bipolar I disorder in the Romanian population. Psychiatric Genetics, 2008, 18 (5) :240-247, IF=2,35.

12.   Steinhausen H-Ch, Grigoroiu-Serbanescu M, Boyadjieva S, Neumärker K J, Winkler Metzke C (2008). Course and Predictors of Rehospitalization in Adolescent Eating Disorders in a Multi-site Study. International Journal of Eating Disorders , 41 : 29-36, IF = 2,87.

13.   Grigoroiu-Serbanescu M., Nöthen MM, Ohlraun S, Propping P, Maier W, Wickramaratne P, Georgescu MJ, Prelipceanu D, Grimberg M, Sima D, Rietschel M. Family History Influences Age of Onset in Bipolar I Disorder in Females but not in Males. American Journal of Medical Genetics – Neuropsychiatric Genetics, 133B, 2005, 6-11 . IF = 3,23.

14.   Grigoroiu-Serbanescu M., Magureanu S., Milea S., Dobrescu I., Marinescu E. Modest familial aggregation of eating disorders in restrictive anorexia nervosa with adolescent onset in a Romanian sample. European Child and Adolescent Psychiatry, Suppl 1, 12, 2003, .47-53, , IF = 3,69.

15.   Steinhausen HC, Boyadjieva S, Grigoroiu-Serbanescu M, Neumärker K-J. The outcome of adolescent eating disorders. Findings from an international collaborative study.

16.   European Child and Adolescent Psychiatry, Suppl 1, 12, 2003, 91-98. IF = 3,69.

17.   Grigoroiu-Serbanescu M, Martinez M, Nöthen MM, Propping P. Different Familial Transmission Patterns in Bipolar I Disorder with Onset Before and After Age 25. American Journal of Medical Genetics – Neuropsychiatric Genetics, 105, 2001, 765-773. IF = 4,156.

18.   Steinhausen H. Ch., Boyadjeva S., Grigoroiu-Serbanescu M., Seidel R., Winkler-Metzke C., Transcultural outcome study of adolescent eating disorders, Acta Psychiatrica Scandinavica, 101, 2000, 60-66, IF = 4,85.

19.   Grigoroiu-Serbanescu M., Martinez M., Nothen M.M., Propping P., Milea S., Mihailescu R., Patterns of parental transmission and familial aggregation models in bipolar affective disorder. American Journal of Medical Genetics - Neuropsychiatric Genetics, 81, 397-404, 1998 . IF = 4,15.

20.   Grigoroiu-Serbanescu M., Wickramaratne P.J., Hodge S.E., Milea S., Mihailescu R., Genetic anticipation and imprinting in bipolar I illness. The British Journal of Psychiatry, 170, 162-166, 1997. IF = 6,61.

21.   Grigoroiu-Serbanescu M., Nothen M., Propping P., Poustka F., Magureanu S., Vasilescu R., Marinescu E., Ardelean V., Clinical evidence for genomic imprinting in the bipolar I disorder, ActaPsychiatrica Scandinavica, 1995, 92, 365-370 . IF = 4,85.

22.   Grigoroiu-Serbanescu M, A trial to apply the concept of imprinting to the manic-depressive illness, The Romanian Journal of Neurology and Psychiatry, 30, 4, 1992, 265-277.

23.   Grigoroiu-Serbanescu M., Christodorescu D., Magureanu S., Jipescu I, Totoescu A., Marinescu E., Ardelean V., Popa S., Adolescent offspring of endogenous unipolar depressive parents and of normal parents, Journal of Affective Disorders, 21, 1991, 185-198. IF = 3,29.

24.   Grigoroiu-Serbanescu M, ChristodorescuD, Totoescu A, Jipescu I., Marinescu E., Ardelean V., Depressive disorders and depressive personality traits in offspring aged 10-17 of bipolar I and normal parents, Journal of Youth and Adolescence, 20, 2, 1991, 135-148; IF = 2,69.

25.   Grigoroiu-Serbanescu M., Christodorescu D, Jipescu I., Totoescu A., Marinescu E., Ardelean V., Psychopathology in children aged 10-17 of bipolar parents: psychopathology rate and correlates of the severity of the psychopathology, Journal of Affective Disorders, 16, 1989, 167-179 . IF = 3,29.