Dr. Hui Jin

The Feinstein Institute for Medical Research, Northwell Health, United States

Reasearch Fellow

Email: hjin1@northwell.edu

Qualifications

2017 Postdoc, Neutrophils Heterogeneity, The Feinstein Institute for Medical Research, United States

2013 Ph.D., Stroke Microcirculatory Disorders, Southern Medical University, China

2003 B.S. and M.S., Clinical ,Medicine, Sun Yat-sen University, China

Publications (Selected)

1. Jin H, Aziz M, Atsushi M, et al. Antigen-presenting aged neutrophils induce CD4+ T cells to exacerbate inflammation in sepsis. J Clin Invest. 2023, 133(14):e164585.
2. Qiuping Zhou, Lanfen Lin, Haiyan Li, Yichen Li, Nan Liu 1, Huifang Wang, Shuqi Jiang, Qian Li, Zhuo Chen, Yiyan Lin , Hui Jin, Yiyu Deng. Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat. J Neurosci Res. 2023,101(6):930-951(co-corresponding author).
3. Royster W, Jin H, Wang P, Aziz M. Extracellular CIRP decreases Siglec-G expression on B-1a cells skewing them towards a pro-inflammatory phenotype in sepsis. Mol Med. 2021, 27(1):55.
4. Gurien SD, Aziz M, Jin H, et al. Extracellular microRNA 130b-3p Inhibits eCIRP-induced Inflammation. EMBO Rep.2020,21(1): e48075.
5. Jin H, Aziz M, Ode Y, Wang P. CIRP Induces Neutrophil Reverse Transendothelial Migration in Sepsis. SHOCK. 2019. 51(5):548-556.
6. Jin H, Zhao X, Li R, et al. Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways. PLoS One. 2018, 13(1):e0192083.
7. Jin H, Chen Y, Ding C, et al. Microcirculatory Disorders and Protective Role of Xuebijing in Severe Heat Stroke. Sci Rep. 2018, 8(1):4553.
8. Hui Jin, Zhipeng Li, Xiaohua Guo, et al. Microcirculatory Disorders and Protective Role of Anti-oxidant in Severe Heat Stroke: A Rat Study. Shock. 2016, 46(6):688-695.
9. Murao A, Arif A, Brenner M, Denning NL, Jin H, Takizawa S, Nicastro B, Wang P*, Aziz M*. Extracellular CIRP and TREM-1 axis promotes ICAM-1-Rho-mediated NETosis in sepsis. FASEB J. 2020, 34(7):9771-9786.
10. Chen K, Murao A, Takiawa S, Arif A, Jin H, Jiang J, Aziz M*, Wang P*. Inhibition of efferocytosis by eCIRP-inducedneutrophil extracellular traps. J Immunol. 2021,206(4):797-906.
11. Honghe Luo, Hui Jin, et al，Cyclooxygenase-2 Up-regulates Vascular Endothelial Growth Factor via a Protein Kinase C Pathway in Non-small Cell Lung Cancer. J Exp Clin Cancer Res.2011，30（1）：6.
12. Gurien SD, Aziz M, Jin H, Wang H, He M, Al-Abed Y, Nicastro JM, Coppa GF, Wang P. Extracellular microRNA 130b-3p inhibits eCIRP-induced inflammation. EMBO Rep. 2020 Jan 7;21(1):e48075. doi: 10.15252/embr.201948075. Epub 2019 Nov 14. PMID: 31724825; PMCID: PMC10563445.
13. Ode Y, Aziz M, Jin H, Arif A, Nicastro JG, Wang P. Cold-inducible RNA-binding Protein Induces Neutrophil Extracellular Traps in the Lungs during Sepsis. Sci Rep. 2019 Apr 18;9(1):6252. doi: 10.1038/s41598-019-42762-1. PMID: 31000768; PMCID: PMC6472421.
14. Jin H, Tang LQ, Pan ZG, Peng N, Wen Q, Tang YQ, Su L. Ten-year retrospective analysis of multiple trauma complicated by pulmonary contusion. Mil Med Res. 2014 May 1;1:7. doi: 10.1186/2054-9369-1-7. PMID: 25722865; PMCID: PMC4336115.
15. Chen K, Murao A, Arif A, Takizawa S, Jin H, Jiang J, Aziz M, Wang P. Inhibition of Efferocytosis by Extracellular CIRP-Induced Neutrophil Extracellular Traps. J Immunol. 2021 Feb 15;206(4):797-806. doi: 10.4049/jimmunol.2000091. Epub 2020 Dec 30. PMID: 33380498; PMCID: PMC7854515.
16. Zhao X, Li R, Jin H, Jin H, Wang Y, Zhang W, Wang H, Chen W. Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways. PLoS One. 2018 Jan 26;13(1):e0192083. doi: 10.1371/journal.pone.0192083. PMID: 29373584; PMCID: PMC5786317.
17. Pan Z, Shao Y, Dong W, Liu C, Chen Y, Jin H, Tang L, Qiu J, Su L. Xuebijing attenuates hypotension through the upregulation of angiotensin II type 1 receptor-associated protein 1 in rats suffering from heat stroke. Int J Mol Med. 2014 Dec;34(6):1699-705. doi: 10.3892/ijmm.2014.1950. Epub 2014 Sep 29. PMID: 25270312.
18. Jin H, Li Z, Guo X, Tong H, Liu Z, Chen Y, Su L, Huang Q. Microcirculatory Disorders and Protective Role of Antioxidant in Severe Heat Stroke: A Rat Study. Shock. 2016 Dec;46(6):688-695. doi: 10.1097/SHK.0000000000000623. PMID: 27058049.
19. Zhou Q, Lin L, Li H, Li Y, Liu N, Wang H, Jiang S, Li Q, Chen Z, Lin Y, Jin H, Deng Y. Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat. J Neurosci Res. 2023 Jun;101(6):930-951. doi: 10.1002/jnr.25170. Epub 2023 Jan 31. PMID: 36720002.
20. Chen K, Murao A, Arif A, Takizawa S, Jin H, Jiang J, Aziz M, Wang P. Inhibition of Efferocytosis by Extracellular CIRP-Induced Neutrophil Extracellular Traps. J Immunol. 2021 Feb 15;206(4):797-806. doi: 10.4049/jimmunol.2000091. Epub 2020 Dec 30. PMID: 33380498; PMCID: PMC7854515.

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