Use of traditional Chinese medicine in HIV/AIDS in China

Jian Wang, Wen Zou, Ying Liu

.

DOI: 10.4236/jbise.2010.38111                

Abstract

This paper gives a general introduction of HIV/AIDS treatment with Traditional Chinese Medicine (TCM) in China during the past 20 years. Although the role of TCM in treatment of HIV/AIDS is promising, there is still a long way to go.

Keywords

HIV/AIDS; Traditional Chinese Medicine (TCM)

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	Wang, L., Wang, N., Wang, L., Li, D., Jia, M., Gao, X., et al. (2009) The 2007 estimates for people at risk for and living with HIV in China: Progress and challenges. Journal of Acquired Immune Deficiency Syndromes, 50(4), 414-418.
[2]	Luo, S.D. and Ju, P. (2006) Compared traditional Chinese medicine and western medicine to treat AIDS. Journal of Henan University of Chinese Medicine, 21(3), 1-3.
[3]	Lam, T.L., Lam, M.L., Au, T.K., et al. (2000) A comparison of human immunodeficiency virus type-I protease inhibition activities by the aqueous and methanol extracts of Chinese medicine herbs. Life Science, 67(23), 2889-2896.
[4]	Au, T.K., Lam, T.L., Ng, T.B., et al. (2001) A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicine herbs. Life Science, 68(14), 1687-1694.
[5]	Kobayashi, Y., Watanabe, M., Ogihara, J., et al. (2000) Inhibition of HIV-1 reverse transcriptase by methanol extracts of commercial herbs and spices. Journal of the Japanese Society for Food Science and Technology, 47(8), 642-645.
[6]	McGrath, M.S., Santulli, S. and Gaston, I. (1990) Effects of GLQ223 on HIV replication in human monocyte/ macrophages chronically infected in vitro with HIV. AIDS Research and Human Retroviruses, 6(8), 1039-1043.
[7]	McGrath, M.S., Hwang, K.M., Caldwell, S.E., et al. (1989) GLQ223: An inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage. Proceedings of the National Academy of Sciences, 86(8), 2844-2848.
[8]	Byers, V.S., Levin, A.S., Malvino, A., et al. (1994) A phase II study of effect of addition of trichosanthin to zidovudine in patients with HIV disease and failing antiretroviral agents. AIDS Research and Human Retroviruses, 10(4), 413-420.
[9]	Mayer, R.A., Sergios, P.A., Coonan, K., et al. (1992) Trichosanthin treatment of HIV-induced immune dysregulation. European Journal of Clinical Investigation, 22(2), 113-122.
[10]	Byers, V.S., Levin, A.S., Waites, L.A., et al. (1990) A phase I/II study of trichosanthin treatment of HIV disease. AIDS, 4(12), 1189-1196.
[11]	Kahn, J.O., Kaplan, L.D., Gambertoglio, J.G., et al. (1990) The safety and pharmacokinetics of GLQ223 in subjects with AIDS and AIDS-related complex: A phase I study. AIDS, 4(12), 1197-1204.
[12]	Gai, L., Song, C.Q., Hu, Z.B., et al. (2001) Review of anti-HIV plants. Foreign Medical Sciences, 23, 139.
[13]	He, J.H. and Mai, E.D. (2004) Review of AIDS treatment with Chinese medicine. Chinese Pharmaceutical and Clinical Research, 4, 454.
[14]	Chen, X., Yang, L., Zhang, N., et al. (2003) Shikonin, a component of Chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. Antimicrobial Agents and Chemotherapy, 47(9), 2810-2816.
[15]	Zhang, Z.J. (1995) The phagocytosis of HIV infected cells by Xiao chaihu tang extracts. Foreign Medical Sciences, 17, 64.
[16]	Guan, C.F. (1995) Experimental study of SIV infected monkey model treatment by Zhongyan-1. Chinese Journal of Information on Traditional Chinese Medicine, 2, 42-46.
[17]	Kusum, M., Klinbuayaem, V., Bunjob, M., et al. (2004) Preliminary efficacy and safety of oral suspension SH, combination of five Chinese medicinal herbs, in people living with HIV/AIDS; the phase I/II study. Journal of the Medical Association of Thailand, 87(9), 1065-1070.
[18]	Wu, H., Zhang, F.J., Yao, C., et al. (2004) Clinical study of Tangcao tablet in treating HIV/AIDS. Compilation of Theses of Treatment and Research on AIDS, 3, 95-103.
[19]	Wang, J., Yang, F.Z., Zhao, M., et al. (2006) Randomized double-blinded and controlled clinical trial on treatment of HIV/AIDS by Zhongyan-4. Chinese Journal of Integrative Medicine, 12(1), 6-11.
[20]	Shi, D. and Peng, Z.L. (2003) Randomized double blind placebo paralleled clinical research on HIV/AIDS with Qiankunning tablets. Study Journal of Traditional Chinese Medicine, 21, 1472-1474.
[21]	Chen, J.Z. (2009) Xiaomi granule on HIV/AIDS patients with oral candidacies. Guangming Journal of Chinese Medicine, 24, 633-636.