Dr. Ravin Natain

Chemical and Materials Engineering

University of Alberta, Canada

Associate Professor

Email: Narain@ualberta.ca

Qualifications

2001 Ph.D., University of Mauritius, Mauritius

1997 B.Sc., University of Mauritius, Mauritius

Publications

1. Marya Ahmed, Phanphen Wattanaarsakit, Ravin Narain “Cationic Glyco-Nanogels for Epidermal Growth Factor Receptor (EGFR) specific siRNA delivery in Ovarian Cancer Cells” Polymer Chemistry, (2013).
2. Marya Ahmed, Saul Mamba, Xiao-Hong Yang, James Dwarka, Piyush Kumar, Ravin Narain “Synthesis and Evaluation of Polymeric Gold Glyco-Conjugates as Anti-Cancer Agents” Bioconjugate Chemistry (2013).
3. Manraj Jawanda, Benjamin F. L. Lai, Jayachandran N. Kizhakkedathu, Kazuhiko Ishihara, Ravin Narain “Linear and Hyperbranched Phosphorylcholine based Homopolymers for Blood Biocompatibility” Polymer Chemistry (2013) 4, 3140-3146.
4. Marya Ahmed, Ravin Narain “Cell Line Dependent Uptake and Transfection Efficiencies of PEI-Anionic Glycopolymer Systems” Biomaterials (2013) 34, 4368-4376.
5. Yohei Kotsuchibashi, Roman Agustin, jinyong lu, Dennis Hall, Ravin Narain "Temperature, pH, and Glucose Responsive Gels via Simple Mixing of Boroxole- and Glyco-Based Polymers", ACS Macro Letters (2013) 2, 260-264.
6. Yinan Wang, Ravin Narain and Yang Liu “Study of bacterial adhesion on glycopolymers-treated gold surfaces using quartz crystal microbalance with dissipation (QCM-D)” Biofouling, (2013), submitted
7. Marya Ahmed, Ravin Narain “Recent Advances in the Preparation of Glycopolymer Bioconjugates” European Polymer Journal (2013), Invited review (submitted)
8. N. Idota, M. Ebara, Y. Kotsuchibashi, R. Narain, T. Aoyagi “Novel temperature-responsive polymer brushes with carbohydrate residues facilitate selective adhesion and collection of hepatocytes” Science and Technology of Advanced Materials, (2012). 13, 064206
9. Rajesh Sunasee, Ravin Narain “Glycopolymers and Glyconanoparticles for Biomolecular Recognition Processes and Vaccines Development” Macromolecular Bioscience, Accepted (2012) (Invited Review).
10. Marya Ahmed, Ravin Narain “Progress of RAFT based Polymers in the Field of Gene Delivery” Progress in Polymer Science, (2012) Accepted, published online.
11. Rajesh Sunasee, Phanphen Watanaarsakit, Marya Ahmed, Farah Lollmahomed, Ravin Narain “Biodegradable and Non-Toxic Nanogels as Non-Viral Gene Delivery Systems” Bioconjugate Chemistry, (2012). 23, 1925-1933
12. Marya Ahmed, Ravin Narain “Intracellular Delivery of DNA and Enzyme in Active Form using Degradable Carbohydrate based Nanogels” Molecular Pharmaceutics, (2012), Accepted, published online.
13. Marya Ahmed, Manraj Jawanda, Kazuhiko Ishihara, Ravin Narain “Impact of the Nature, Size and Chain Topologies of Carbohydrate-Phosphorylcholine Polymeric Gene Delivery Systems” Biomaterials, (2012), 31, 7858-7870.
14. Yohei Kotsuchibashi, Yiyao Zhang, Ravin Narain “Fabrication of FITC-doped Silica Nanoparticles and Study of their Cellular Uptake in the Presence of Lectins: Journal of Biomedical Materials Research, (2012), Accepted, in press.
15. Yohei Kotsuchibashi, Mitsuhiro Ebara, Aoyagi Takao, Ravin Narain “Fabrication of Doubly-Responsive Polymer Functionalized Silica Nanoparticles via a Simple Thiol-Ene Click Chemistry” Polymer Chemistry, (2012), 3, 2545-2550.
16. Marya Ahmed, Ravin Narain “The Effect of Molecular Weight, Compositions and Lectin Type on the Properties of Hyperbranched Glycopolymers as Non-Viral Gene Delivery Systems” Biomaterials (2012), 33, 3990-4001.
17. Yohei Kotsuchibashi, Mitsuhiro Ebara, Naokazu Idota, Ravin Narain and Takao Aoyagi “A ‘smart’ approach towards the formation of multifunctional nano-assemblies by simple mixing of block copolymers having a common temperature sensitive segment” Polym. Chem. (2012) 3, 1150-1157. (Highlight Polymer Chemistry: Paper of the Week, May 2012)
18. Marya Ahmed, Benjamin F. L. Lai, Jayachandran N. Kizhakkedathu, Ravin Narain “Hyperbranched Carbohydrate based Polymers for Blood Biocompatibility” Bioconjugate Chemistry (2012) 23, 1050-1058
19. Jui-Tse Chen, Marya Ahmed, Qingxia Liu, Ravin Narain “Synthesis of Cationic Magnetic Nanoparticles and Evaluation of their Gene Delivery Efficacy in Hep G2 Cells” Journal of Biomedical Materials Research, (2012), 100A, 2342-2347.
20. Ravin Narain, “Rho kinases (ROCKs) in Sepsis-Induced Acute Lung Injury” J Thorac Dis (2011) 4, 12-14 (Editorial)
21. Neha Bhuchar, Rajesh Sunasee, Kazuhiko Ishihara, Thomas Thundat, Ravin Narain “Degradable Thermo-Responsive Nanogels for Proteins Encapsulation and Controlled Release” Bioconjugate Chemistry (2011) 6, 1228-1238.
22. Pavel I. Kitov, Eugenia Paszkiewicz, Joanna M. Sadowska, Zhicheng Deng, Marya Ahmed, Ravin Narain, Thomas P. Griener, George L. Mulvey, Glen D. Armstrong and David R. Bundle, “Impact of the Nature and Size of the Polymeric Backbone on the Ability of Heterobifunctional Ligands to Mediate Shiga Toxin and Serum Amyloid P Component Ternary Complex Formation”, Toxins (2011), 9, 1065-1088.
23. Danielle Brabant, Paul Michael, Farag Bleiblo, Mazen Saleh, Ravin Narain, T.C. Tai, Chilakamarti V. Ramana, Joseph E. Parrillo, Anand Kumar, Aseem Kumar, “Septic sera induces apoptosis and DNA fragmentation factor 40 activation in fibroblasts” Biochemical and Biophysical Research Communications, (2011), In press.
24. Farahnaz Begum Lollmahomed and Ravin Narain, “A Photochemical Approach towards Deposition of Gold Nanoparticles on Functionalized Carbon Nanotubes”, Langmuir, (2011), 27, 12642-12649
25. Xuejuan Wan, Guoying Zhang, Zhishen Ge, Ravin Narain, Shiyong Liu Construction of Polymer-Protein Bioconjugates with Varying Chain Topologies: Polymer Molecular Weight and Steric Hindrance Effects, Chemistry: An Asian Journal, (2011), 6, 2835-2845
26. Marya Ahmed, Ravin Narain “Synthetic Glycopolymer-based Non-Viral Gene Delivery Systems: Evaluation of Polymer Architectures, Compositions and Molecular Weights on Gene Expression” Biomaterials (2011), 32, 5279. 2010
27. Marya Ahmed, Ravin Narain “Rapid Synthesis of Gold Nanorods Using a One-Step Photochemical Strategy” Langmuir (2010), 26, 18392
28. Xiaoze Jiang, Maria Vamvakaki, R. Narain “Copper-Catalyzed Bimolecular Coupling of α,ω-dibromide Functionalized Poly(ε-caprolactone)” Macromolecules (2010), 43, 3228–3232.
29. Xiaoze Jiang, Abdelghani Housni, Guillaume Gody, Paul Boullanger, Marie T. Charreyre, Thierry Delair, Ravin Narain “Synthesis of Biotinylated α-d-Mannoside or N-Acetyl β-d-Glucosaminoside Decorated Gold Nanoparticles: Study of Their Biomolecular Recognition with Con A and WGA Lectins” Bioconjugate Chemistry (2010), 21, 521-530.
30. Xiaoze Jiang, Shiyong Liu, Ravin Narain “Degradable Thermoresponsive Core Cross-Linked Micelles: Fabrication, Surface, Functionalization, and Biorecognition” Langmuir, (2009), 25, 13344–13350.
31. Marya Ahmed, Xiaoze Jiang, Zhicheng Deng and Ravin Narain “Cationic Glyco-Functionalized Single Walled Carbon Nanotubes as Efficient Gene Delivery Vehicles” Bioconjugate Chemistry (2009), 20, 2017–2022
32. Zhicheng Deng, Suqi Li, Xiaoze Jiang and Ravin Narain “Well-Defined Galactose-Containing Multi-Functional Copolymers and Glyconanoparticles for Biomolecular Recognition Processes” Macromolecules, (2009), 42, 6393–6405
33. Marya Ahmed, Zhicheng Deng, and Ravin Narain, “Study of Transfection Efficiencies of Cationic Glyconanoparticles of Different Sizes in Human Cell Line” ACS Applied Materials and Interfaces (2009), 1, 1980–1987
34. Xiaoze Jiang, Marya Ahmed, Zhicheng Deng, and Ravin Narain “Biotinylated Glyco-functionalized Quantum Dots: Synthesis, Characterization, and Cytotoxicity Studies” Bioconjugate Chemistry, (2009). 20, 994 (Top 10 Most Accessed Article in 2009)
35. Xiaoze Jiang, Guoying Zhang, Ravin Narain and Shiyong Liu “Covalently Stabilized Multi-Responsive Four-Layer Nanoparticles Fabricated from Surface ‘Clickable’ Shell Cross-Linked Micelles” Soft Matter (2009), 5, 1530 - 1538
36. Xiaoze Jiang, Guoying Zhang, Ravin Narain and Shiyong Liu “Fabrication of Two Types of Shell Cross-Linked Micelles with “Inverted” Structures in Aqueous Solution from Schizophrenic Water-Soluble ABC Triblock Copolymer via Click Chemistry” Langmuir (2009), 25, 2046-2054 (Highlighted in Nature, 2009)
37. Keshwaree Babooram, Ravin Narain “Fabrication of SWNT/Silica Composites by the Sol-Gel Process” ACS Applied Materials and Interfaces (2009), 1, 181–186.
38. Suchita Kalele, Ravin Narain, Kannan M. Krishnan “Probing Temperature-Sensitive Behavior of pNIPAAm Coated Iron Oxide Nanoparticles Using Frequency Dependent Magnetic Measurements” Journal of Magnetism and Magnetic Materials, (2009), 321, 1377-1380
39. Jianding Ye, Ravin Narain ”Water-Assisted Atom Transfer Radical Polymerization of N-Isopropylacrylamide: Nature of Solvent and Temperature” J. Phys. Chem. B (2009), 113, 767-681.
40. Zhicheng Deng, Marya Ahmed, Ravin Narain “Novel Well-Defined Glycopolymers Synthesized via the Reversible Addition-Fragmentation Chain Transfer Process in Aqueous Media” J. Polym. Sci., Part A: Polym. Chem. (2009), 47, 614-627.
41. Viktoria Kekkonen, Nelson Lafreniere, Mitsuhiro Ebara, Atsuhiro Saito, Yoshiki Sawa and Ravin Narain “Synthesis and Characterization of Biocompatible Magnetic Glyconanoparticles” Journal of Magnetism and Magnetic Materials, (2009) 321 1393
42. Anca Mateescu, Jianding Ye, Ravin Narain and Maria Vamvakaki “Synthesis and Characterization of Novel Glycosurfaces via ATRP” Soft Matter (2009), 5, 1621 - 1629
43. Abdelghani Housni, Marya Ahmed, Shiyong Liu, Ravin Narain “Monodisperse Protein Stabilized Gold Nanoparticles via a Simple Photochemical Process” J. Phys. Chem. C (2008), 112, 12282-12290.
44. Zhicheng Deng, Hassen Bouchékif, Keshwaree Babooram, Abdelghani Housni, Nankishoresing Choytun, and Ravin Narain “Facile Synthesis of Controlled-Structure Primary Amine-Based Methacrylamide Polymers via the Reversible Addition-Fragmentation Chain Transfer Process” J. Polym. Sci., Part A: Polym. Chem. (2008), 46, 4984-4996.
45. Zhishen Ge, Jian Xu, Danlu Wu, Ravin Narain, Shiyong Liu “pH-Switchable Complexation Between Double Hydrophilic Heteroarm Star Copolymer and a Cationic Block Polyelectrolyte” Macromol. Chem. Phys. (2008), 209, 754-763.
46. Keshwaree Babooram, Bejoy Francis, Rabin Bissessur, Ravin Narain “Novel (amide-imide)-silica Composites through the Sol-gel Process” Composites Science and Technology (2008), 68, 617-624. 2007
47. Ravin Narain, Abdelghani Housni, Guillaume Gody, Paul Boullanger, Marie-Therese Charreyre*, Thierry Delair, “Preparation of Biotinylated Glyconanoparticles via a Photochemical Process and Study of Their Bioconjugation to Streptavidin” Langmuir (2007), 23, 12835-12841
48. Hassen Bouchekif, Ravin Narain, “Reversible Addition Fragmentation Chain Transfer Polymerization of N-isopropylacrylamide: A Comparison between a Fast and a Slow Initiator” J. Phys. Chem. B. (2007), 111, 11120-11126.

Expertise (fields)

Drug and Gene Delivery, Polymer Science and Engineering, Biomaterials, Bio-Nanotechnology, Carbohydrate Science

Profile Details

Last Updated: June, 2013.

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