YanPing Yu

University of Pittsburgh, U.S.A.

Assistant Professor of Pathology

Email: ypyu@pitt.edu

Qualifications

1995 Ph.D., University of Maryland at Baltimore, School of Medicine, USA

1987 M.Sc., Sun Yat-Sen University of Medical Science, China

1982 M.D. Medicine, Guangzhou Medical Institute, China

Publications (Selected)

1. Zhang-Hui Chen, Yan P. Yu, George Michalopoulos, Joel Nelson and Jian-Hua Luo (2015). The DNA replication licensing factor miniature chromosome maintenance 7 is essential for RNA splicing of epidermal growth factor receptor, c-met and platelet derived growth factor receptor. Journal of Biological Chemistry, J Biol Chem. 2015 Jan 16;290(3):1404-11.
2. Jian-Hua Luo, Silvia Liu, Ze-Hua Zuo, Rui Chen, George C. Tseng, Yan P. Yu (2015). Discovery and Classification of Fusion Transcripts in Prostate Cancer and Normal Prostate Tissue. Am J Pathol 185(7):1834-45.
3. Zuo ZH, Yu YP, Ding Y, Liu S, Martin A, Tseng G, Luo JH (2015). Oncogenic Activity of miR-650 in Prostate Cancer Is Mediated by Suppression of CSR1 Expression. Am J Pathol 185(7):1991-9.
4. Chen ZH, Yu YP, Michalopoulos G, Nelson J, Luo JH (2015). The DNA replication licensing factor miniature chromosome maintenance 7 is essential for RNA splicing of epidermal growth factor receptor, c-Met, and platelet-derived growth factor receptor. J Biol Chem. 2015 Jan 16;290(3):1404-11.
5. Yan P. Yu, Ying Ding, Zhanghui Chen, Silvia Liu, Amantha Michalopoulos, Rui Chen, Zulfiqar G. Gulzar, Bing Yang, Kathleen Cieply, Alyssa Luvison, Bao-Guo Ren, James D. Brooks, David Jarrard, Joel B. Nelson, George Michalopoulos, George C. Tseng and Jian-Hua Luo (2014). Novel fusion transcripts associate with progressive prostate cancer, Am J Pathol. 2014 Oct;184(10):2840-9..
6. Yan P. Yu, Amantha Michalopoulos, Ding Ying, George Tseng and Jian-Hua Luo (2014). High Fidelity Copy Number Analysis of Formalin-Fixed and Paraffin-Embedded Tissues Using Affymetrix Cytoscan HD Chip. PLOS ONE 9(4):e92820.
7. Lindsey M. Kelly, Guillermo Barila, Pengyuan Liu, Viktoria N Evdokimova, Sumita Trivedi, Federica Panebianco, Manoj Gadhi, Sally E. Carty Steven Hodak, Jianhua Luo, Sanja Dacic, Yan P Yu, Marina N Nikiforova, Robert L. Ferris, Daniel L. Altschuler and Yuri E Nikiforov (2014). Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. The Proceedings of National Academy of Sciences of USA, 111(11):4233-8.
8. Yan P. Yu, Ying Ding, Rui Chen, Serena G. Liao, Bao-Guo Ren, Amantha Michalopoulos, George Michalopoulos, Joel Nelson, George C. Tseng and Jian-Hua Luo (2013). Whole genome methylation sequencing reveals distinct impact of differential methylations on genetranscription in prostate cancer. Am J Pathol 183, 1960-1970.
9. Jian-Hua Luo, Ying Ding, Rui Chen, George Michalopoulos, Joel Nelson, George Tseng, and Yan P. Yu (2013). Genome-wide methylation analysis of prostate tissues reveals global methylation patterns of prostate cancer. Am J Pathol.182(6):2028-2036.
10. Yu-Chen Han, Zhong-Liang Zheng, Ze-Hua Zuo, Yan P. Yu, Rui Chen, George C. Tseng, Joel B. Nelson and Jian-Hua Luo (2013). Metallothionein 1h Tumor Suppressor Activity in Prostate Cancer Is Mediated By Euchromatin Methyltransferase 1. J Pathol. 230(2):184-93.
11. Xi-Yue Zhang, Lang-Zhu Tang, Bao-Guo Ren, Yan P. Yu, Joel Nelson, George Michalopoulos and Jian-Hua Luo (2013). Interaction of MCM7 and RACK1 for activation of MCM7 and cell growth. American Journal of Pathology, 182:796-805.
12. Zhong-Liang Zheng, Lang-Zhu Tang, Yan P. Yu, George Michalopoulos and Jian-Hua Luo (2012). Interaction of CSR1 with XIAP reverses inhibition of caspases and accelerates cell death. American journal of Pathology, 181, 463-71.
13. Hui Wang, Katherine Luo, Lang-Zhu Tan, Bao-Guo Ren, Li-Qun Gu, George Michalopoulos, Jian-Hua Luo, and Yan P. Yu (2012). p53-Induced-Gene 3 Mediates Cell Death Induced by Glutathione Peroxidase 3. Journal of Biological Chemistry 287, 16890-902.
14. Yan P. Yu, Chi Song, George Tseng, Baoguo Ren, William Laframboise, George Michalopoulos, Joel Nelson and Jian-Hua Luo (2012). Genome abnormalities precede prostate cancer and predict clinical relapse. American Journal of Pathology, 180, 2240-8.
15. Michael Nalesnik, George Tseng Ying Ding, Guo-Sheng Xiang, Zhong-liang Zheng, Yan Ping Yu, J. Wallis Marsh, George Michalopoulos and Jian-Hua Luo (2012). Gene Deletions and Amplifications in Human Hepatocellular Carcinomas: Correlation with Hepatocyte Growth Regulation. American Journal of Pathology 180, 1495-508.

Profile Details

http://path.upmc.edu/Personnel/Faculty/Yu.htm

Last Updated: 2015-07-01