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Biography

Dr. Dimitrios Farmakis

University of Athens Medical School, Greece


E-mail: dimitrios_farmakis@yahoo.com


Qualifications


2003  PhD, University of Athens Medical School

1996  MD, University of Athens Medical School


Publications (Selected)

  1. Aessopos Α, Farmakis D, Karagiorga M, Rombos Ι, Loucopoulos D. Pseudoxanthoma Elasticum Lesions and Cardiac Complications as Contributing Factors for Strokes in β-Thalassemia Patients. Stroke 1997;28:2421-2424.
  2. Aessopos A, Karabatsos F, Farmakis D, Katsantoni A, Hatziliami A, Youssef J, Karagiorga M. Pregnancy in well-treated β-thalassemic patients: Outcome for mothers and newborns. Am J Obstet Gynecol 1999;180:360-365.
  3. Aessopos Α, Farmakis D, Tassiopoulos T, Taktikou H, Perakis A, Stamatelos G, Loucopoulos D. Doppler-determined tricuspid pressure gradient in individuals with normal pulmonary function and tricuspid regurgitation. J Am Soc Echocardiogr 2000;13:645-649.
  4. Aessopos A, Farmakis D, Karagiorga M, Voskaridou E, Hatziliami A, Joussef J, Rombos J, Loukopoulos D. Cardiac involvement in thalassemia intermedia: A multicenter study.Blood 2001;97:3411-3416.
  5. Aessopos A, Tsironi M, Vassiliadis I, Farmakis D, Fountos A, Voskaridou E, Perakis A, Defteraios S, Loutradi A, Loukopoulos D. Exercise-induced myocardial perfusion abnormalities in sickle β-thalassemia: Tc-99m tetrofosmin gated SPECT imaging study. Am J Med 2001;111:355-360.
  6. Aessopos A, Farmakis D, Loukopoulos D. Elastic tissue abnormalities resembling pseudoxanthoma elasticum in β thalassemia and the sickling syndromes. Blood 2002;99:30-35.
  7. Deftereos S, Lambrinoudakis C, Andriopoulos P, Farmakis D, Aessopos A. A Java-based Electronic Healthcare Record Software for beta-Thalassaemia. J Med Internet Res 2001;3:e33 (URL: http://www.jmir.org/2001/4/e33/).
  8. Aessopos A, Politou M, Farmakis D, Sideris P, Grapsa A, Andreopoulos A, Kalahanis N, Karagiorga M. Staphylococcus aureus abscess of the spleen in a b thalassemia patient.Scand J Infect Dis 2002;34:466-468.
  9. Aessopos A, Farmakis D, Loukopoulos D. Elastic tissue abnormalities in inherited hemolytic syndromes. Eur J Clin Invest 2002;32:640-642.
  10. Aessopos Α, Grapsa Α, Sideris P, Farmakis D, Politou M, Paikos S, Aroni K. Oral paraneoplastic pemphigus associated with renal malignancy: A case report. Acta Dermato-Venereol 2003;83:72-73.
  11. Farmakis D, Moyssakis I, Perakis A, Rombos Y, Deftereos S, Giakoumis A, Polymeropoulos E, Aessopos A. Unstable angina associated with coronary arterial calcification in a thalassemia intermedia patient with a pseudoxanthoma elasticum-like syndrome. Eur J Haematol 2003;70:64-66.
  12. Farmakis D, Giakoumis A, Polymeropoulos E, Aessopos A. Pathogenetic aspects of immune deficiency in thalassemia. Med Sci Monit 2003; 9:RA 19-22.
  13. Pectasides D, Pectasides M, Farmakis D, Bountouroglou N, Nikolaou M, Koumpou M, Mylonakis N, Kosmas C. Oxaliplatin plus high dose leucovorin and 5-fluorouracil as salvage treatment in advanced breast cancer. Phase II study. Ann Oncol 2003;14:537-42.
  14. Pectasides D, Mylonakis N, Farmakis D, Nikolaou M, Koumpou M, Katselis I, Gaglia A, Kostopoulou V, Karabelis A, Kosmas C. Irinotecan and gemcitabine in patients with advanced non-small cell lung cancer, previously treated with cisplatin-based chemotherapy. A Phase II study. Anticancer Res 2003;23:4205-11.
  15. Pectasides D, Skarlos D, Dimopoulos A, Farmakis D, Pectasides M, Fountzilas G, Aravantinos G. Two-cycles of carbopltin-based adjuvant chemotherapy for high-risk clinical stage I and stage IM non-seminomatous germ cell tumours of the testis: A HeCOG Trial. Anticancer Res 2003;23:4239-44.
  16. Pectasides D, Pectasides M, Farmakis D, Nikolaou M, Koumpou M, Kostopoulou V, Mylonakis N. Testicular function in patients with testicular cancer treated with bleomycin-etoposide-carboplatin (BEC90) combination chemotherapy. Eur Urol 2004;45:187-93.
  17. Pectasides D, Pectasides M, Farmakis D, Aravantinos G, Nikolaou M, Koumpou M, Gaglia A, Kostopoulou V, Mylonakis N, Skarlos D. Gemcitabine and Oxaliplatin (GEMOX) in patients with cisplatin-refractory germ cell tumors. A Phase II study. Ann Oncol 2004;15: 493-7.
  18. Farmakis D, Deftereos S, Giakoumis A, Polymeropoulos E, Aessopos A. Rupture of chordae tendineae in patients with β-thalassemia. Eur J Haematol 2004;72:296-8.
  19. Aessopos A, Farmakis D. Comments on the European guidelines on cardiovascular disease prevention. Eur Heart J 2004;25:619.
  20. Pectasides D, Pectasides M, Farmakis D, Aravantinos G, Nikolaou M, Koumpou M, Gaglia A, Kostopoulou V, Mylonakis N, Economopoulos T, Raptis S. Oxaliplatin and irinotecan plus granulocyte-colony stimulating factor as third-line treatment in relapsed or cisplatin-refractory germ-cell tumor patients. A phase II study. Eur Urol 2004;46:216-21.
  21. Pectasides D, Pectasides M, Farmakis D, Gaglia A, Koumarianou A, Nikolaou M, Koumpou M, Kountourakis P, Papaxoinis G, Mitrou P, Economopoulos T, Raptis SA. Oxaliplatin plus high dose leucovorin and 5-fluorouracil (FOLFOX 4) in platinum-resistant, taxane-pretreated: ovarian cancer. A phase II study. Gynecol Oncol 2004;95:165-72.
  22. Deftereos S, Farmakis D, Papadogianni A, Besleme B, Diamanti-Kandarakis E, Polymeropoylos E, Georgonikou D, Aessopos A. Waldenstrom's macroglobulinemia developing in a patient with multiple sclerosis: coincidence or association? Mult Scler 2004;10:598-600.
  23. Aessopos A, Farmakis D, Hatziliami A, Fragodimitri C, Karabatsos F, Joussef J, Mitilineou E, Diamanti-Kandaraki E, Meletis J, Karagiorga M. Cardiac status in well-treated patients with thalassemia major. Eur J Haematol 2004;73:359-66.
  24. Farmakis D, Vesleme V, Papadogianni A, Tsaftaridis P, Kapralos P, Aessopos A. Aneurysmatic dilatation of ascending aorta in a patient with β-thalassemia and a Pseudoxanthoma Elasticum-like syndrome. Ann Hematol 2004;83:596-9.
  25. Aessopos A, Farmakis D, Tsironi M, Deftereos S, Tassiopoulos S, Konstantopoulos K, Rombos J, Papalambros E. Hemodynamic assessment of splenomegaly in beta-thalassemia patients undergoing splenectomy. Ann Hematol 2004;83:775-8.
  26. Aessopos A, Deftereos S, Farmakis D, Corovesis C, Tassiopoulos S, Tsironi M, Georgonikou D, Moisakis J. Cardiovascular adaptation to chronic anemia in the elderly: An echocardiographic study. Clin Invest Med 2004;27:265-73.
  27. Tsironi M, Korovesis K, Farmakis D, Deftereos S, Aessopos A. Hypoparathyroidism and heart failure in thalassemic patients: A case report. Pediatr Endocrinol Rev 2004;2 Suppl 2:310-2.
  28. Tsironi M, Deftereos S, Andriopoulos P, Farmakis D, Meletis J, Aessopos A. Reversal of heart failure in thalassaemia major by combined chelation therapy: A case report. Eur J Haematol 2005;74:84-5.
  29. Pectasides D, Farmakis D, Nikolaou M, Kanakis I, Kostopoulou V, Papaconstantinou I, Karamanos NK, Economopoulos T, Raptis SA. Diagnostic value of bone remodeling markers in the diagnosis of bone metastases in patients with breast cancer. J Pharm Biomed Anal 2005;37:171-176.
  30. Pectasides D, Farmakis D, Koumarianou A. The role of neoadjuvant chemotherapy in the treatment of advanced ovarian cancer. Oncology 2005;68:64-70.
  31. Pectasides D, Pectasides M, Farmakis D, Kostopoulou V, Nikolaou M, Gaglia A, Koumpou M, Mylonakis N, Xiros N, Economopoulos T, Raptis SA. Comparison of docetaxel and docetaxel-irinotecan combination as second-line chemotherapy in advanced non-small-cell lung cancer: a randomized phase II trial. Ann Oncol 2005;16:294-9.
  32. Farmakis D, Horeftaki P, Kavouklis M, Aessopos A. Visual loss associated with angioid streaks in sickle thalassemia. Haematologica 2005;90:ECR02.
  33. Pectasides D, Fountzilas G, Aravantinos G, Kalofonos HP, Efstathiou E, Salamalekis E, Farmakis D, Skarlos D, Briasoulis E, Economopoulos T, Dimopoulos MA. Advanced stage mucinous epithelial ovarian cancer: The Hellenic Cooperative Oncology Group experience. Gynecol Oncol 2005;97:436-41.
  34. Parissis JT, Farmakis D, Kremastinos DT. Anti-inflammatory effects of levosimendan in decompensated heart failure: Impact on weight loss and anemia. Am J Cardiol 2005;95:923-4.
  35. Pectasides D, Nikolaou M, Farmakis D, Kanakis I, Gaglia A, Kountourakis P, Karamanos NK, Economopoulos T, Raptis SA. Clinical value of bone remodeling markers in patients with bone metastases treated with zoledronic acid. Anticancer Res 2005;25:1457-63.
  36. Aessopos A, Farmakis D, Deftereos S, Tsironi M, Polonifi A, Moyssakis I, Diamanti-Kandaraki E, Papalambros E. Cardiovascular effects of splenomegaly and splenectomy in B-thalassemia. Ann Hematol 2005; 84:353-7.
  37. Aessopos A, Farmakis D, Deftereos S, Tsironi M, Tassiopoulos S, Moyssakis J, Karagiorga M. Thalassemia heart disease: a comparative evaluation of thalassemia major and thalassemia intermedia. Chest 2005;127:1523-30.
  38. Grapsa A, Farmakis D, Variami E, Polonifi A, Diamanti-Kandaraki E, Papalambros E, Aroni K, Aessopos A. Hereditary hemorrhagic telangiectasia associated with vitiligo, autoimmune thyroiditis, iridocyclitis and a myelodysplastic syndrome. Clin Exper Dermatol 2005;30:448-50.
  39. Parissis JT, Panou F, Farmakis D, Adamopoulos S, Filippatos G, Paraskevaidis I, Venetsanou K, Lekakis J, Kremastinos DT. Effects of levosimendan on markers of left ventricular diastolic function and neurohormonal activation in patients with advanced heart failure. Am J Cardiol 2005;96:423-6.
  40. Farmakis D, Polymeropoulos E, Polonifi A, Deftereos S, Giakoumi X, Floudas H, Grapsa A, Aessopos A. Myelodysplastic syndrome associated with multiple autoimmune disorders. Clin Rheumatol 2005;24:428-30.
  41. Pectasides D, Aravantinos G, Fountzilas G, Kalofonos C, Efstathiou E, Karina M, Pavlidis N, Farmakis D, Economopoulos T, Dimopoulos MA. Brain metastases from epithelial ovarian cancer. The Hellenic Cooperative Oncology Group (HeCOG) experience and review of the literature. Anticancer Res 2005;25:3553-8.
  42. Tsironi M, Polonifi K, Deftereos S, Farmakis D, Andriopoulos P, Moyssakis I, Aessopos A. Transfusional hemosiderosis and combined chelation therapy in sickle thalassemia.Eur J Haematol 2005;75:355-358.
  43. Farmakis D, Pectasides M, Pectasides D. Recent advances in conventional-dose salvage chemotherapy in patients with cisplatin-resistant or refractory testicular germ cell tumors. Eur Urol 2005;48:400-7.
  44. Parissis JT, Filippatos G, Farmakis D, Adamopoulos S, Paraskevaidis I, Kremastinos DT. Levosimendan for the treatment of acute heart failure syndromes. Expert OpinPharmacother 2005;6:2741-51.
  45. Aessopos A, Farmakis D. Pulmonary hypertension in b-thalassemia. Ann N Y Acad Sci 2005;1054:342-9.
  46. Tassiopoulos S, Deftereos S, Konstantopoulos K, Farmakis D, Tsironi M, Kyriakidis M, Aessopos A. Does heterozygous beta-thalassemia confer a protection against coronarydisease? Ann N Y Acad Sci 2005;1054:467-70.
  47. Pectasides D, Fountzilas G, Aravantinos G, Kalofonos C, Efstathiou H, Farmakis D, Skarlos D, Pavlidis N, Economopoulos T, Dimopoulos MA. Advanced stage clear-cell epithelial ovarian cancer: the Hellenic Cooperative Oncology Group experience. Gynecol Oncol 2006;102:285-91.
  48. Farmakis D, Polonifi A, Deftereos S, Tsironi M, Papaioannou I, Aessopos A. Aortic valve replacement in a patient with thalassemia intermedia. Ann Thorac Surg 2006;81:737-9.
  49. Aessopos A, Kati M, Tsironi M, Polonifi E, Farmakis D. Exchange blood transfusions for the treatment of leg ulcerations in thalassemia intermedia. Haematologica 2006;91:ECR11
  50. Aessopos A, Tassiopoulos S, Farmakis D, Moyssakis I, Kati M, Polonifi K, Tsironi M. Extramedullary hematopoiesis-related pleural effusion: the case of beta-thalassemia. Ann Thorac Surg 2006;81:2037-43.