Biography

Dr. Ghanshyam D. Heda

Mississippi University for Women, USA
Assistant Professor


Email: gheda@as.muw.edu

Qualifications

2008 Assistant Professor, Mississippi University for Women, Biology

1996 Professor, The University of Tennessee Health Sciences Center, Medicine
1983 Ph.D., Osmania University, Hyderabad, Genetics

1978 M.Sc., Osmania University, Hyderabad, Genetics

1975 B.Sc., Osmania University, Hyderabad, Biology


Publications (Selected)

  1. Heda, G. D. and Roberts L. K., Role of tissue-type plasminogen activator in salicylic acid-induced sloughing of human corn tissue. J. Am Podiatr Med Assoc (JAPMA), 98, 345-352, 2008. [This article won the 2009 William J. Stickel Award in podiatric medicine research].
  2. Norez C., Heda G. D., Jensen T. Ilana Kogan I., Hughes L. K., Auzanneau C., Dérand R., Bulteau-Pignoux L., Li C., Ramjeesingh M., Li H., Sheppard D. N., Bear C. E., Riordan J. R., Becq F., Determination of CFTR chloride channel activity and pharmacology using radiotracer flux methods. J. Cystic Fibrosis, 3, 119-121, 2004.
  3. Roxo-Rosa M., Davezac N., Bensalem N., Majumdar M., Heda G. D., Simas A., Penque D., Amaral M. D., Lukacs G. L., Edelman A., Proteomics techniques for cystic fibrosis research, J. Cystic Fibrosis, 3, 85-89, 2004.
  4. Farinha, C. M., Penque D., Roxo-Rosa M., Lukacs G., Dormer R., McPherson M., Pereira M., Bot A. G. M., Jorna H., Willemsen R., De Jonge H., Heda G. D., et al. Biochemical methods to assess CFTR expression and membrane localization, J. Cystic Fibrosis, 3, 73-77, 2004.
  5. Mendes, F., Farinha M., Roxo-Rosa M.,Fanen P., Edelman A., Dormer R., McPherson M., Davidson H., Puchelle E., De Jonge H., Heda G. D., et al. Antibodies for CFTR studies, J. Cystic Fibrosis, 3, 69-72, 2004.
  6. Ann E., Farinha C. M., Heda G. D., Harris A., Amaral M. D., Mouchel N., Non-PCR methods for the analysis of CFTR transcripts,  J. Cystic Fibrosis, 3, 25-28, 2004.
  7. Anabela S., Ramalho, A. S., Beck S., Carlos M., Farinha C. M., Clarke L. A., Heda G. D., Steiner B., Sanz J., Sabina G., Amaral M. D., Harris A., Tzetis M.,  Methods for RNA extraction, cDNA preparation and analysis of CFTR transcripts. J. Cystic Fibrosis, 3, 11-15, 2004.
  8. Yoshimura K., Anzai C., Iizuka S., Eto Y., Heda G. D., Molecular biological study of action mechanism of macrolide antibiotics on CFTR. J. Antibiot, 2003, 56, Suppl. A: 117-200.
  9. Naren A. P., Cobb B., Li C., Roy K., Nelson D., Heda G. D., Lion J., Kirk K. L., Sorscher E. J., Hanrahan J., Clancy J. P., A macromolecular complex of 2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA, Proc. of Natl. Acad. Sci., USA, 100(1), 342-346, 2003.
  10. Heda G. D., Tanwani M., Marino C. R., The F508 mutation shortens the biochemical half-life of plasma Membrane CFTR in polarized epithelial cells, Am. J. Physiol Cell Physiol, 280, C166-C174, 2001.
  11. Mahan, J. T., Heda G. D., Rao R. H., Mansbach II C. M., The intestine expresses pancreatic triacylglycerol lipase: Regulation by dietary lipid, Am. J. Physiol Gastrointest Liver Physiol, 280, G1187-G1196, 2001.
  12. Heda G. D. and Marino C. R., Surface expression of the cystic fibrosis transmembrane conductance regulator mutant, F508, is markedly upregulated by combination treatment with sodium butyrate and low temperature, Biochemi. Biophysi. Res. Comm., 271, 659-664, 2000.
  13. Heda G. D., Kehoe K. J., Mahdi F., Schmaier A. H., Phosphatase 2A participates in interferon's induced upregulation of C1 Inhibitor mRNA expression, Blood, 87, 2831-2838, 1996.
  14. Schamier, A. H., Amenta S., Xiong T., Heda G. D., Gewirtz AM: Expression of platelet C1 Inhibitor, Blood, 82, 465-474, 1993.
  15. Heda, G. D., Henion T. R., Galili U., A simple in vitro site directed mutagenesis of concatamerized cDNA by inverse polymerase chain reaction, Nucleic Acids Research, 20, 5241-5242. 1992.
  16. Heda G. D., Merdente S., Weiner L., Schmaier A. H., Gamma interferon increases in vitro and in vivo expression of C1 Inhibitor, Blood, 75, 2401-2407, 1990.
  17. Schmaier A. H., Murray S., Heda G. D., Farber A., Kuo A., McCrae K., Cines D. B., Synthesis and expression of C1 Inhibitor by human umbilical vein endothelial cells, J. Biol. Chem., 264, 18173-18179, 1989.
  18. Heda G. D. and Madigan M. T., Purification and characterization of the thermal stable ribulose-1,5-bisphosphate carboxylase/oxygenase from the thermophilic purple bacterium, Chromatium tepidum, Eur. J. Biochem, 183, 313-319, 1989.
  19. Heda G. D. and Madigan M. T., Thermal properties and oxygenase activity of ribulose-1,5-bisphosphate carboxylase from the thermophilic purple bacterium, Chromatium tepidum, FEMS Microbiol Lett., 51, 45-50, 1988.
  20. Reddy, M. K., Heda G. D., Reddy J. K., Purification and characterization of amylase from rat pancreatic acinar carcinoma, Biochem. J., 242, 681-687, 1987.
  21. Heda G. D. and Madigan M. T., Amino acid metabolism and lack of diazotrophy in the thermophilic anoxygenic phototroph Chloroflexus aurantiacus, J. Gen. Microbiol., 132 (9), pp. 2469-2473, 1986.
  22. Heda G. D. and Madigan M. T., Aspects of nitrogen fixation in Chlorobium, Arch. Microbiol., 143, 330-336, 1986.
  23. Heda G. D. and Reddy G. M., Studies on the inheritance of amylose content and gelatinisation temperature in rice (Oryza sativa L), Genet. Agrar., 40 (1), 1-8, 1986.
  24. Heda G. D. and Reddy G. M., Inheritance studies of morphological and quality characteristics in rice, SABRAO Journal, 16 (2), 153-156, 1984.
  25. Heda G. D. and Reddy G. M., Studies on protein content and yield levels in rice, Theor Appl. Genet., 69 (1), 93-95, 1984.
  26. Heda G. D. and Reddy G. M., Genetic analysis of cooking quality of rice, J. Cytol. Genet., 19, 38-42, 1984.

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