Dr. Jean-Christophe Cintrat

Laboratoire de Chimie Combinatoire et de Criblages à Haut Débit, France

Email: jean-christophe.cintrat@cea.fr

Qualifications

1995 Ph.D., Nantes university

1991 DEA, university of Nantes, organic chemistry

1990 Master, university of Orléans, Chemistry

Publications (Selected)

1. Rivière, G., Oueslati, S., Gayral, M., Créchet, J.-B., Nhiri, N., Jacquet, E., Jean-Christophe Cintrat, J.-C., Giraud, F., van Heijenoort, C., Lescop, E., Pethe, S., Bogdan, I., Naas, T., Guittet, T., Morellet, N.(2020), NMR Characterization of the Influence of Zinc(II) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-β-Lactamase-1 and on the Binding with Flavonols as Inhibitors, ACS Omega 5(18), 10466-10480.
2. Forrester, A., Rathjen, S.J., Daniela Garcia-Castillo, M., Bachert, C., Couhert, A., Tepshi, L., Pichard, S., Martinez, J., Munier, M., Sierocki, R., Renard, H.-F., Augusto Valades-Cruz, C., Dingli, F., Loew, D., Lamaze, C., Cintrat, J.-C., Linstedt, A.D., Gillet, D., Barbier, J., Johannes, L., (2020), Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2, Nat. Chem. Biol., 16 (3), 327-336.
3. Ernouf, G., Chirkin, E., Rhyman, L., Ramasami, P., Cintrat, J.-C., (2020), Photochemical Strain-Release-Driven Cyclobutylation of C(sp3)-Centered Radicals, Angew. Chem. Int. Ed., 59 (7), 2618-2622.
4. Mahtal, N., Wu, Y., Cintrat, J.-C., Barbier, J., Lemichez, E., Gillet, D., (2020), Revisiting old ionophore lasalocid as a novel inhibitor of multiple toxins, Toxins, 12 (1), 26.
5. Wu, Y., Boulogne, C., Carle, S., Podinovskaia, M., Barth, H., Spang, A., Cintrat, J.-C., Gillet, D., Barbier, J., (2020), Regulation of endo-lysosomal pathway and autophagic flux by broad-spectrum antipathogen inhibitor ABMA, FEBS Journal, 1-38.