Prof. Joseph S. Merola

Virginia Polytechnic Institute and State University, USA

Email: jmerola@vt.edu

Qualifications 

1978   Ph.D., Massachusetts Institute of Technology
1974   B.S., Carnegie-Mellon University

Publications (Selected)

1. The Chemistry of mer-(Me3P)3Ir(H)(2-furyl)Cl:  Preferential Reaction of an Alkyne with an Ir-C Bond in the Presence of an Ir-H Bond.  Selnau, H.E.;  Merola, J.S.  Organometallics, 1993, 12, 3800-3802.
2. Synthesis, Structural Characterization and Reactivity of the (2-Benzoato)iridium(III) Hydride Complex [mer-(Me3P)3Ir(2-O2CC6H5)(H)][PF6].  Ladipo, F.T.;  Merola, J.S.  Inorg. Chem, 1993, 32, 5201-5205.
3. An Unusual Trimerization Reaction of an Alkyne on Iridium.  Le, T.X.;  Selnau, H.E.;  Merola, J.S. J. Organomet. Chem., 1994, 468, 257-264
4. Crystal Structures of 30-Crown-10 and Its Tetrahydrate.  Bheda, M. C.;  Merola, J.S.;  Woodward, W.A.;  Vasudevan, V.;  Gibson, H.  J. Org. Chem. 1994, 59, 1694-1702.
5. Additions of Carbanions to tris-(trimethylphosphine)(cyclooctadiene)iridium(I) Chloride:  Three Different Modes of Reaction Depending on the Nature of the Carbanion.  Frazier, J. F.;  Anderson, F. E.;  Clark, R.; Merola, J.S.  Inorg. Chim. Acta  1994, 222, 135-143.
6. Syntheses, X-ray Structures, Complexation, and Thermal Stability Studies of Bis(5-carbomethoxy-1,3-phenylene)-3x+2)-crown-x Compounds.  Delaviz, Y.;  Merola,  J.S.;  Berg, M.A.G.;  Gibson, H.W.  J. Org. Chem., 1995, 60, 516-522.
7. Intramolecular Diels-Alder Reactions of the Furan Diene (IMDAF);  Rapid Construction of Highly Functionalized Isoquinoline Skeletons.  Hudlicky, T.;  Butora, G.; Fearnley, S.; Gum, A.; Persichini, P.J.; Stabile, M.;   Merola, J.S. J. Chem. Soc., Perkin Trans. 1, 1995, 2393-8.
8. Additions of Carbanions to tris-(trimethylphosphine)(cyclooctadiene)iridium(I) Chloride:  Three Different Modes of Reaction Depending on the Nature of the Carbanion.  Frazier, J. F.;  Anderson, F. E.;  Clark, R. Merola, J.S.  Inorg. Chim. Acta  1994, 222, 135-143. (This was an invited paper for a special volume.)
9. Microbial Oxidation of Aromatics in Enantiocontrolled synthesis.  Part 1.  Expedient and General Asymmetric Synthesis of Ionositols and Carbohydrates via an Unusual Oxidation of a Polarized Diene with Potassium Permanganate.  Hudlicky, T.;  Mandel, M.;  Rouden, J.;  Lee, R.S.; Bachmann, B.;  Dudding, T.; Yost, K.J.;  Merola, J.S.  J. Chem. Soc., Perkin Trans 1, 1994, 1553-67
10. Pentamethylcyclopentadienylrhodium bis-carboxylates: monohapto carboxylate coordination, dihapto carboxylate coordination, and water coordination to CpRh. Boyer,  P.M.;  Roy, C. P.;  Bielski, J.M.;  Merola, J.S.  Inorg. Chim. Acta, 1996, 245, 7-15.
11. Synthesis and Properties of Cholesteryl Esters Bearing 32- and 16-Membered Crown Ethers.  Nagvekar, D.S.;  Delaviz, Y.;  Prasad, A.;  Merola, J.S.;  Marand, H.;  Gibson, H.W.  J. Org. Chem., 1996, 61, 1211-1218.
12. Synthesis and Characterization of aminocarboxylato iridium(III) complexes.  Kooti, M.; Merola, J.S.  Iran. J.  Chem. Chem. E.,  1997, 16, 4-10.
13. Organic Chemistry at an Iridium Center:  Unusual Bond-Making and Bond-Breaking Reactions.  Merola, J.S.  Curr. Org. Chem., 1997, 1, 14.
14. A Study of the Complexation of bis(m-Phenylene) Crown Ethers and Secondary Ammonium Ions.   Bryant, W.S.;  Guzei, I.A.; Rheingold, A.L.; Merola, J.S.; Gibson, H.W. J. Org. Chem., 1998,  63, 16.
15. Synthesis of succinimido[3,4-b]indane and 1,2,3,4,5,6-hexahydro-1,5-methano-3-benzazocine-2,4-dione by sequential alkylation and intramolecular arylation of enolates derived from N,N,N ' N '-tetramethylbutanediamides and N,N,N ' N '-tetramethylpentanediamides.  Dandekar SA, Greenwood SN, Greenwood TD, Mabic S, Merola JS, Tanko JM, Wolfe JF  J. Org. Chem., 1999,  64, 1543.
16. Williams, Russell B.; Norris, Andrew; Slebodnick, Carla; Merola, Joseph; Miller, James S.; Andriantsiferana, Rabodo; Rasamison, Vincent E.; Kingston, David G. I.   Cytotoxic Sesquiterpene Lactones from Vernonia pachyclada from the Madagascar Rainforest.    Journal of Natural Products, 2005,  68(9),  1371-1374.
17. Tyree, William S.; Slebodnick, Carla; Spencer, Mary C.; Wang, Guangbin; Merola, Joseph S.; Yee, Gordon T.   Structure-property correlations in a family of decamethylmetallocenium charge-transfer salt magnets using dialkyl dicyanofumarates as the one-electron acceptors: Ferromagnetism versus metamagnetism.    Polyhedron, 2005,  24(16-17),  2133-2140.
18. Roy, Christopher P.; Huff, Lisa A.; Barker, Nick A.; Berg, Michael A. G.; Merola, Joseph S..   Iridium(III) hydrido amino acid compounds: Chiral complexes and a helical extended lattice.    Journal of Organometallic Chemistry, 2006,  691(10),  2270-2276.
19. Gibson, Harry; Berg, Michael; Dickson, Jennifer; Lecavelier, Pierre; Wang, Hong; Merola,Joseph.  Diastereomeric reissert compounds of isoquinoline and 6,7-dimethoxy-3,4-dihydroisoquinoline in stereoselective Synthesis. Journal of Organic Chemistry, 2007, 72(15), 5759-5770.
20. Gibson, Harry; Wang, Hong; Slebodnick, Carla; Merola, Joseph; Kassell, W. Scott; Rheingold, Arnold. Isomeric 2,6-pyridino-cryptands based on dibenzo-24-crown-8.  Journal of Organic Chemistry, 2007, 72(9), 3381-3393.