Biography

Prof. Charles Joel Rosser

University of Central Florida, USA

 

Email: charles.rosser@orlandohealth.com

 

Qualifications

 

1994 Ph.D., Robert Wood Johnson Medical School, USA

1990 B.Sc., Fairleigh Dickinson University, USA

 

Publications (Selected)

  1. Rosser CJ, Goodison S. Novel approach for oral cancer biomarker discovery. Biomark Med. 2010 Aug;4(4):495-6.
  2. Rosser CJ, Goodison S. From gene to protein expression: improving prognostication of DCIS. Biomark Med. 2010 Aug;4(4):496-7.
  3. Rosser CJ, Goodison S. CD24, a promising biomarker in NSCLC. Biomark Med. 2010 Aug;4(4):495.
  4. Rosser CJ, Goodison S. Today's discoveries to tomorrow's care: cancer biomarkers revisited. Foreword. Biomark Med. 2010 Aug;4(4):491-3.
  5. Rosser CJ, Goodison S. Research highlights. Biomark Med. 2010 Aug;4(4):495-7.
  6. Rosser CJ, Goodison S. Today's discoveries to tomorrow's care: cancer biomarkers revisited. Biomark Med. 2010 Aug;4(4):491-3.
  7. Bovio IM, Al-Quran SZ, Rosser CJ, Algood CB, Drew PA, Allan RW.Smoothelin immunohistochemistry is a useful adjunct for assessing muscularis propria invasion in bladder carcinoma. Histopathology. 2010 Jun;56(7):951-6.
  8. Arakawa M, Nakamura K, Yamada Y, Rosser CJ, Tobiume M, Saito H, Hasegawa T, Honda N. Association between gefitinib and hemorrhagic cystitis and severely contracted bladder: a case report. BMC Urol. 2010 Feb 26;10:6.
  9. Villicana P, Whiting B, Goodison S, Rosser CJ. Urine-based assays for the detection of bladder cancer. Biomark Med. 2009 Jun 1;3(3):265.P
  10. Rosser CJ. Editorial comment. Urology. 2010 Jan;75(1):132; author reply 132-3. No abstract available.
  11. Nakamura K, Yamada Y, Rosser CJ, Aoki S, Taki T, Honda N. Holmium YAG laser ablation of a hemangioma involving a lower pole renal calyx - using the new-generation flexible ureteroscope URF type P5: a case report. Cases J. 2009 Jun 17;2:7780.
  12. Goodison S, Rosser CJ, Urquidi V. Urinary proteomic profiling for diagnostic bladder cancer biomarkers. Expert Rev Proteomics. 2009 Oct;6(5):507-14.
  13. Rosser CJ. Editorial Comment. J Urol. 2009 Sep 15.
  14. CJ. Utility of serial urinary cytology in the initial evaluation of the patient with microscopic hematuria. BMC Urol. 2009 Sep 10;9:12.
  15. Sippel KH, Boehlein SK, Sakai Y, Quirit JG, Agbandje-McKenna M, Rosser CJ, McKenna R. Cloning, expression, purification, crystallization and preliminary X-ray analysis of Mycoplasma genitalium protein MG289. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt 9):910-2.
  16. Namiki K, Goodison S, Porvasnik S, Allan RW, Iczkowski KA, Urbanek C, Reyes L, Sakamoto N, Rosser CJ. Persistent exposure to Mycoplasma induces malignant transformation of human prostate cells. PLoS One. 2009 Sep 1;4(9):e6872.
  17. Rosser CJ, Gaar M, Porvasnik S. Molecular fingerprinting of radiation resistant tumors: can we apprehend and rehabilitate the suspects? BMC Cancer. 2009 Jul 9;9:225.
  18. Porvasnik S, Sakamoto N, Kusmartsev S, Eruslanov E, Kim WJ, Cao W, Urbanek C, Wong D, Goodison S, Rosser CJ. Effects of CXCR4 antagonist CTCE-9908 on prostate tumor growth. Prostate. 2009 Sep 15;69(13):1460-9.
  19. Anai S, Sakamoto N, Sakai Y, Tanaka M, Porvasnik S, Urbanek C, Cao W, Goodison S, Rosser CJ. Dual targeting of Bcl-2 and VEGF: A potential strategy to improve therapy for prostate cancer. Urol Oncol. 2009 Jul 2.
  20. Dahm P, Rosser CJ, McKiernan JM. Quality of care for testis cancer. Urol Oncol. 2009 Jul-Aug;27(4):448-53. Review.
  21. Urbanek C, Turpen R, Rosser CJ. Radical Prostatectomy: Hospital volumes and surgical volumes - does practice make perfect? BMC Surg. 2009 Jun 6;9(1):10.
  22. Sakai Y, Goodison S, Cao W, Urquidi V, Namiki K, Porvasnik S, Urbanek C, Rosser CJ.VEGF induces expression of Bcl-2 and multiple signaling factors in microvascular endothelial cells in a prostate cancer model. World J Urol. 2009 Jun 4.
  23. Rosser CJ, Liu L, Sun Y, Villicana P, McCullers M, Porvasnik S, Young PR, Parker AS, Goodison S. Bladder Cancer-Associated Gene Expression Signatures Identified by Profiling of Exfoliated Urothelia. Cancer Epidemiol Biomarkers Prev. 2009 Feb 3. [Epub ahead of print]
  24. Turpen R, Rosser CJ. Focal therapy for prostate cancer: revolution or evolution? BMC Urol. 2009 Apr 23;9(1):2.
  25. Namiki K, Kasraeian A, Yacoub S, Rosser CJ. Blunt apical dissection during anatomic radical retropubic prostatectomy. BMC Res Notes. 2009 Feb 6;2:20.
  26. Sippel KH, Robbins AH, Reutzel R, Boehlein SK, Namiki K, Goodison S, Agbandje-McKenna M, Rosser CJ, McKenna R. Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis.J Bacteriol. 2009 Apr;191(8):2585-92.
  27. Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R. Design of a Carbonic Anhydrase IX Active-Site Mimic To Screen Inhibitors for Possible Anticancer Properties (dagger) (double dagger). Biochemistry. 2009 Jan 26.
  28. Namiki K, Kasraeian A, Yacoub S, Rosser CJ. Blunt apical dissection during anatomic radical retropubic prostatectomy BMC Research Notes 2009, 2:20.
  29. Sippel KH, Robbins AH, Reutzel R, Domsic J, Boehlein SK, Govindasamy L, Agbandje-McKenna M, Rosser CJ, McKenna R. Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37. Acta Crystallographica. 2008 64(11): 1172-1178.
  30. Sakai Y, Goodison S, Kusmartsev S, Fletcher B, Eruslanov E, Cao W, Porvasnik S, Namiki K, Anai S, Rosser CJ. Bcl-2 mediated modulation of vascularization in prostate cancer xenografts. Prostate. 2008 Dec 23.
  31. Rosser CJ. Prostate Cancer - To screen, or not to screen, is that the question? BMC Urol. 2008 Dec 23;8(1):20.
  32. Kusmartsev S, Eruslanov E, Kübler H, Tseng T, Sakai Y, Su Z, Kaliberov S, Heiser A, Rosser C, Dahm P, Siemann D, Vieweg J. Oxidative stress regulates expression of VEGFR1 in myeloid cells: link to tumor-induced immune suppression in renal cell carcinoma. J Immunol. 2008 Jul 1;181(1):346-53.
  33. Tomioka A, Tanaka M, De Velasco MA, Anai S, Takada S, Kushibiki T, Tabata Y, Rosser CJ, Uemura H, Hirao Y. Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation. Mol Cancer Ther. 2008 Jul;7(7):1864-70.
  34. Pendleton J, Curry RW, Kaserian A, Chang M, Anal S, Nakamura K, Abdoush P, Rosser CJ. Knowledge and attitudes of primary care physicians regarding prostate cancer screening. J Natl Med Assoc. 2008 Jun;100(6):666-70.
  35. Pendleton J, Hopkins C, Anai S, Nakamura K, Chang M, Grissett A, Rosser CJ. Prostate cancer knowledge and screening attitudes of inner-city men. J Cancer Educ. 2008;23(3):172-9.
  36. Cao W, Shiverick KT, Namiki K, Sakai Y, Porvasnik S, Urbanek C, Rosser CJ. Docetaxel and bortezomib downregulate Bcl-2 and sensitize PC-3-Bcl-2 expressing prostate cancer cells to irradiation. World J Urol. 2008 Jul 2.
  37. Pendleton JM, Tan WW, Anai S, Chang M, Hou W, Shiverick KT, Rosser CJ. Phase II Trial of Isoflavone in prostate specific antigen recurrent prostate cancer after previous local therapy. BMC Cancer. 2008 May 11;8(1):132.
  38. Cao W, Yacoub S, Shiverick KT, Namiki K, Sakai Y, Porvasnik S, Urbanek C, Rosser CJ. Dichloroacetate (DCA) sensitizes both wild-type and over expressing Bcl-2 prostate cancer cells in vitro to radiation. Prostate. 2008 Aug 1;68(11):1223-31.
  39. Anai S, Nakamura K, Pendleton J, Gaar M, Yacoub S, Rosser CJ. The feasibility of watchful waiting in inner-city men with newly diagnosed localized prostate cancer.  J Health Care Poor Underserved. 2008 Feb;19(1):164-70.
  40. Kassouf W, Brown GA, Shetty A, Hazle JD, Stafford RJ, Rosser CJ, Stephens C, Tinkey PT, Pisters LL. An in vivo orthotopic canine model to evaluate distribution of intraprostatic injectate: implications for gene therapy and drug delivery for prostate cancer. Urology. 2007 Oct;70(4):822-5.
  41. Anai S, West CS, Chang M, Nakamura K, Pendleton J, Rosser CJ. Outcomes of men who present with elevated serum PSA (>20 ng/mL) to an inner-city hospital. J Natl Med Assoc. 2007 Aug;99(8):895-9.
  42. Anai S, Shiverick K, Medrano T, Nakamura K, Goodison S, Brown BD, Rosser CJ. Downregulation of BCL-2 induces downregulation of carbonic anhydrase IX, vascular endothelial growth factor, and pAkt and induces radiation sensitization. Urology. 2007 Oct;70(4):832-7.
  43. Goodison S, Nakamura K, Iczkowski KA, Anai S, Boehlein SK, Rosser CJ. Exogenous mycoplasmal p37 protein alters gene expression, growth and morphology of prostate cancer cells. Cytogenet Genome Res. 2007;118(2-4):204-13.
  44. Goodison S, Rosser CJ. Bladder Cancer Associated Glycoprotein Signatures revealed by Urinary Proteomic Profiling. J Proteome Res. 2007 Jul;6(7):2631-9. Epub 2007 May 23.
  45. Nakamura K, Kasraeian A, Anai S, Pendleton J, Rosser CJ. Positive surgical margins at radical prostatectomy: importance of intra-operative bladder neck frozen sections. Int Braz J Urol. 2007 Nov-Dec;33(6):746-51.
  46. Nakamura K, Kasraeian A, Yacoub SM, Pendleton JM, Anai S, Rosser CJ. The use of enoxaparin to prevent venous thromboembolism in patients undergoing radical retropubic prostatectomy: feasibility and utility. Int Braz J Urol. 2007 May-Jun;33(3):347-52; discussion 352-4.
  47. Anai S, Tanaka M, Shiverick KT, Kim W, Takada S, Boehlein S, Goodison S, Mizokami A, Rosser CJ. Increased expression of COX-2 correlates with resistance to Radiation in human prostate adenocarcinoma cells. J Urol. 2007 May;177(5):1913-7.
  48. Anai S, Brown BD, Nakamura K, Goodison S, Hirao Y, Rosser CJ. Irradiation of Human Prostate Cancer Cells Increases Uptake of Antisense Oligodeoxynucleotide.  Int J Radiat Oncol Biol Phys. Int J Radiat Oncol Biol Phys. 2007 Jul 15;68(4):1161-8.
  49. Anai S, Goodison S, Shiverick K, Hirao Y, Brown BD, Rosser CJ. Knock-down of Bcl-2 by antisense oligodeoxynucleotides induces radiosensitization and inhibition of angiogenesis in human PC-3 prostate tumor xenografts Mol Cancer Ther 2007 6: 101-111.
  50. Namiki K, Rosser CJ. Neoadjuvant therapy and prostate cancer: what a urologist should know. Curr Opin Urol. 2007 May;17(3):188-93.

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