Advances in Disorders of Sex Development

Disorders of sex development, sometimes referred to as disorders of sex differentiation or differences of sex development, are medical conditions involving the reproductive system. More specifically, these terms refer to "congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical."The term has been controversial, and research has shown that affected people experience a negative impact, with the terminology impacting choice and utilization of health care providers. The World Health Organization and many medical journals still reference DSDs as intersex traits or conditions.

Components of the Book:
  • Chapter 1
    The pattern of disorders of sex development in Vietnamese children
  • Chapter 2
    Fertility options and challenges for patients with cytogenetic infertility & disorders of sex development
  • Chapter 3
    Congenital adrenal hyperplasia patient perception of ‘disorders of sex development’ nomenclature
  • Chapter 4
    Submicroscopic copy-number variations associated with 46, XY disorders of sex development
  • Chapter 5
    Targeted next-generation sequencing identification of mutations in patients with disorders of sex development
  • Chapter 6
    Familial forms of disorders of sex development may be common if infertility is considered a comorbidity
  • Chapter 7
    Current models of care for disorders of sex development – results from an International survey of specialist centres
  • Chapter 8
    Disorders of sex development: insights from targeted gene sequencing of a large international patient cohort
  • Chapter 9
    Sex differences in mood disorders: perspectives from humans and rodent models
  • Chapter 10
    Sex-different abnormalities in the right second to fourth digit ratio in Japanese individuals with autism spectrum disorders
Readership: Students, academics, teachers and other people attending or interested in Disorders of Sex Development.
Masafumi Kon, Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan

Raja Brauner, Fondation Ophtalmologique Adolphe de Rothschild and Université Paris Descartes, Paris, France

Andreas Kyriakou, Developmental Endocrinology Research Group, School of Medicine, University of Glasgow, Glasgow, UK

Stefanie Eggers, Murdoch Childrens Research Institute, Melbourne, Australia

Marianne L Seney, Department of Psychiatry, Translational Neuroscience Program, University of Pittsburgh, Pittsburgh, USA

Yuko Okamoto, Research Center for Child Mental Development, University of Fukui, Fukui, Japan

and more...
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