Advances in Rheumatoid Arthritis Drugs

Rheumatoid arthritis (RA) is a long-lasting autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. The disease may also affect other parts of the body. While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body’s immune system attacking the joints. There is no cure for RA, but treatments can improve symptoms and slow the progress of the disease. Disease-modifying treatment has the best results when it is started early and aggressively. The goals of treatment are to minimize symptoms such as pain and swelling, to prevent bone deformity and to maintain day-to-day functioning.

 

In the present book, twelve typical literatures about rheumatoid arthritis drugs published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, genetics, epidemiology, virology, etc. We hope this book can demonstrate advances in rheumatoid arthritis drugs as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Co-stimulation Therapy in Rheumatoid Arthritis: Today and Tomorrow
  • Chapter 2
    Early Medication Use in New-Onset Rheumatoid Arthritis May Delay Joint Replacement: Results of a Large Population-Based Study
  • Chapter 3
    Usability and Acceptability of the Abatacept Pre-Filled Autoinjector for the Subcutaneous Treatment of Rheumatoid Arthritis
  • Chapter 4
    Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Anti- Oncostatin M Monoclonal Antibody in Rheumatoid Arthritis: Results from Phase II Randomized, Placebo-Controlled Trials
  • Chapter 5
    Do COX-2 Inhibitors Provide Additional Pain Relief and Anti-Inflammatory Effects in Patients with Rheumatoid Arthritis Who Are on Biological Disease-Modifying Anti-Rheumatic Drugs and/or Corticosteroids? Post-Hoc Analyses from a Randomized Clinical Trial with Etoricoxib
  • Chapter 6
    Effects of Tofacitinib Monotherapy on Patient-Reported Outcomes in a Randomized Phase 3 Study of Patients with Active Rheumatoid Arthritis and Inadequate Responses to DMARDs
  • Chapter 7
    Efficacy and Safety of Pateclizumab (Anti-Lymphotoxin-α) Compared to Adalimumab in Rheumatoid Arthritis: A Head-to-Head Phase 2 Randomized Controlled Study (the ALTARA Study)
  • Chapter 8
    Enhanced Neutrophil Phagocytic Capacity in Rheumatoid Arthritis Related to the Autoantibodies Rheumatoid Factor and Anti-Cyclic Citrullinated Peptides
  • Chapter 9
    Evaluation of Tocilizumab Therapy in Patients with Rheumatoid Arthritis Based on FDG-PET/CT
  • Chapter 10
    Head-to-Head Comparison of the Safety of Tocilizumab and Tumor Necrosis Factor Inhibitors in Rheumatoid Arthritis Patients (RA) in Clinical Practice: Results from the Registry of Japanese RA Patients on Biologics for Long-Term Safety (REAL) Registry
  • Chapter 11
    The ‘Switch’ Study Protocol: A Randomisedcontrolled Trial of Switching to an Alternative Tumour-Necrosis Factor (TNF)-Inhibitor Drug or Abatacept or Rituximab in Patients with Rheumatoid Arthritis Who Have Failed an Initial TNF-Inhibitor Drug
  • Chapter 12
    Unexpected Arterial Wall and Cellular Inflammation in Patients with Rheumatoid Arthritis in Remission Using Biological Therapy: A Cross-Sectional Study
Readership: Students, academics, teachers and other people attending or interested in Rheumatoid Arthritis Drugs.
Michael Schiff
Department of Rheumatology, University of Colorado, Greenwood Village, Denver, USA

Cristiano S. Moura
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada

Ernest H. Choy
Section of Rheumatology, Cardiff University School of Medicine, Cardiff, Wales, UK

William P. Kennedy
Genentech Research and Early Development, 1 DNA Way, South San Francisco, USA

Ryoko Sakai
Department of Pharmacovigilance, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

Nuria C. Navarro Coy
Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Chapel Allerton Hospital, Leeds, UK

and more...
Copyright © 2006-2024 Scientific Research Publishing Inc. All Rights Reserved.
Top